2-(1-Methylguanidino)acetic acid hydrate

Modify Date: 2024-01-01 17:25:23

2-(1-Methylguanidino)acetic acid hydrate Structure
2-(1-Methylguanidino)acetic acid hydrate structure
Common Name 2-(1-Methylguanidino)acetic acid hydrate
CAS Number 6020-87-7 Molecular Weight 149.148
Density N/A Boiling Point N/A
Molecular Formula C4H11N3O3 Melting Point 292 °C (dec.)(lit.)
MSDS Chinese USA Flash Point N/A

 Use of 2-(1-Methylguanidino)acetic acid hydrate


Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[1].

 Names

Name Creatine monohydrate
Synonym More Synonyms

 2-(1-Methylguanidino)acetic acid hydrate Biological Activity

Description Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Nouioua S, et al. Creatine deficiency syndrome. A treatable myopathy due to arginine-glycine amidinotransferase (AGAT) deficiency. Neuromuscul Disord. 2013 Aug;23(8):670-4.

 Chemical & Physical Properties

Melting Point 292 °C (dec.)(lit.)
Molecular Formula C4H11N3O3
Molecular Weight 149.148
Exact Mass 149.080048
PSA 99.64000
Storage condition Store at RT.
Water Solubility 13 g/L (20 ºC)

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi,Xn
Risk Phrases R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
Safety Phrases S26
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS MB7706000
HS Code 29252000

 Customs

HS Code 2925290090
Summary 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles9

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Creatine is a scavenger for methylglyoxal under physiological conditions via formation of N-(4-methyl-5-oxo-1-imidazolin-2-yl)sarcosine (MG-HCr).

J. Agric. Food Chem. 63(8) , 2249-56, (2015)

Following incubation of methylglyoxal and creatine under physiological conditions, N-(4-methyl-5-oxo-1-imidazolin-2-yl)sarcosine (MG-HCr) was isolated and identified by NMR and mass spectrometry. Due ...

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PLoS ONE 9(10) , e109021, (2014)

Multiple studies suggest creatine mediates anti-oxidant activity in addition to its established role in cellular energy metabolism. The functional significance for the heart has yet to be established,...

 Synonyms

Glycine, N-(aminoiminomethyl)-N-methyl-, hydrate (1:1)
N-Carbamimidoyl-N-methylglycine hydrate (1:1)
Creatine, hydrate
MFCD00071582
EINECS 200-306-6
Creatine monohydrate
2-[carbamimidoyl(methyl)amino]acetic acid,hydrate