防御素 Np1
防御素 Np1结构式
|
常用名 | 防御素 Np1 | 英文名 | Defensin HNP-1 human |
|---|---|---|---|---|
| CAS号 | 99287-08-8 | 分子量 | 3442.030 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C150H228N44O38S6 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
|
Chlamydial plasmid-encoded virulence factor Pgp3 neutralizes the antichlamydial activity of human cathelicidin LL-37.
Infect. Immun. 83 , 4701-9, (2015) Chlamydia trachomatis infection in the lower genital tract can ascend to and cause pathologies in the upper genital tract, potentially leading to severe complications, such as tubal infertility. However, chlamydial organisms depleted of plasmid or deficient i... |
|
|
The antimicrobial peptide LL-37 facilitates the formation of neutrophil extracellular traps.
Biochem. J. 464(1) , 3-11, (2014) NETs (neutrophil extracellular traps) have been described as a fundamental innate immune defence mechanism. During formation of NETs, the nuclear membrane is disrupted by an as-yet unknown mechanism. In the present study we investigated the role of human cath... |
|
|
Neutrophil serine proteinases and defensins in chronic obstructive pulmonary disease: effects on pulmonary epithelium.
Eur. Respir. J. 12 , 1200-1208, (1998) Neutrophils have the capacity to accumulate in high numbers in the lung during infection and inflammation. Because they play an important role in host defence against infection, but may also cause tissue injury, these cells are thought to be involved in the p... |
|
|
IV. Paneth cell antimicrobial peptides and the biology of the mucosal barrier.
Am. J. Physiol. 277 , G257-G261, (1999) The hypothesis that epithelial cells release preformed antibiotic peptides as components of mucosal innate immunity has gained experimental support in recent years. In the mammalian small intestine, Paneth cells secrete granules that are rich in alpha-defensi... |
|
|
Snake Cathelicidin NA-CATH and Smaller Helical Antimicrobial Peptides Are Effective against Burkholderia thailandensis.
PLoS Negl. Trop. Dis. 9 , e0003862, (2015) Burkholderia thailandensis is a Gram-negative soil bacterium used as a model organism for B. pseudomallei, the causative agent of melioidosis and an organism classified category B priority pathogen and a Tier 1 select agent for its potential use as a biologic... |
|
|
Chlamydia-secreted protease CPAF degrades host antimicrobial peptides.
Microbes Infect. 17 , 402-8, (2015) Chlamydia trachomatis infection in the lower genital tract, if untreated, can ascend to the upper genital tract, potentially leading to complications such as tubal factor infertility. The ascension involves cell-to-cell spreading, which may require C. trachom... |