防御素 Np1
防御素 Np1结构式
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常用名 | 防御素 Np1 | 英文名 | Defensin HNP-1 human |
|---|---|---|---|---|
| CAS号 | 99287-08-8 | 分子量 | 3442.030 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C150H228N44O38S6 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
防御素 Np1用途人防御素HNP-1是人中性粒细胞肽(HNPs),参与动脉粥样硬化早期内皮细胞功能障碍发育。防御素HNP-1可调节动脉粥样硬化的生长。 |
| 中文名 | 防御素 Np1 |
|---|---|
| 英文名 | Defensin NP 1 (human reduced) |
| 英文别名 | 更多 |
| 描述 | 人防御素HNP-1是人中性粒细胞肽(HNPs),参与动脉粥样硬化早期内皮细胞功能障碍发育。防御素HNP-1可调节动脉粥样硬化的生长。 |
|---|---|
| 靶点 |
Human Endogenous Metabolite |
| 密度 | 1.5±0.1 g/cm3 |
|---|---|
| 分子式 | C150H228N44O38S6 |
| 分子量 | 3442.030 |
| 精确质量 | 3439.511475 |
| LogP | -8.95 |
| 折射率 | 1.703 |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| 危险品运输编码 | NONH for all modes of transport |
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Chlamydial plasmid-encoded virulence factor Pgp3 neutralizes the antichlamydial activity of human cathelicidin LL-37.
Infect. Immun. 83 , 4701-9, (2015) Chlamydia trachomatis infection in the lower genital tract can ascend to and cause pathologies in the upper genital tract, potentially leading to severe complications, such as tubal infertility. Howev... |
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The antimicrobial peptide LL-37 facilitates the formation of neutrophil extracellular traps.
Biochem. J. 464(1) , 3-11, (2014) NETs (neutrophil extracellular traps) have been described as a fundamental innate immune defence mechanism. During formation of NETs, the nuclear membrane is disrupted by an as-yet unknown mechanism. ... |
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Neutrophil serine proteinases and defensins in chronic obstructive pulmonary disease: effects on pulmonary epithelium.
Eur. Respir. J. 12 , 1200-1208, (1998) Neutrophils have the capacity to accumulate in high numbers in the lung during infection and inflammation. Because they play an important role in host defence against infection, but may also cause tis... |
| HNP-1, Defensin Human Neutrophil Peptide-1 |
| ACYCRIPACIAGERRYGTCIYQGRLWAFCC(Disulfidebridge:2-30,4-19,9-29) |
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