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A-胰凝乳蛋白酶原

A-胰凝乳蛋白酶原结构式
A-胰凝乳蛋白酶原结构式
品牌特惠专场
常用名 A-胰凝乳蛋白酶原 英文名 Chymotrypsinogen
CAS号 9035-75-0 分子量 N/A
密度 N/A 沸点 N/A
分子式 N/A 熔点 N/A
MSDS 美版 闪点 N/A

Protein adsorption, desorption, and aggregation mediated by solid-liquid interfaces.

J. Pharm. Sci. 104 , 1946-59, (2015)

Adsorption of proteins to solid-fluid interfaces is often empirically found to promote formation of soluble aggregates and larger, subvisible, and visible particles, but key stages in this process are often difficult to probe directly. Aggregation mediated by...

Electrodynamic pressure modulation of protein stability in cosolvents.

Biochemistry 52(46) , 8363-73, (2013)

Cosolvents affect structural stability of proteins in aqueous solutions. A clear understanding of the mechanism by which cosolvents impact protein stability is critical to understanding protein folding in a biological milieu. In this study, we investigated th...

Pharmacological inhibition of PAR2 with the pepducin P2pal-18S protects mice against acute experimental biliary pancreatitis.

Am. J. Physiol. Gastrointest. Liver Physiol. 304(5) , G516-26, (2013)

Pancreatic acinar cells express proteinase-activated receptor-2 (PAR2) that is activated by trypsin-like serine proteases and has been shown to exert model-specific effects on the severity of experimental pancreatitis, i.e., PAR2(-/-) mice are protected from ...

Selecting temperature for protein crystallization screens using the temperature dependence of the second virial coefficient.

PLoS ONE 6 , e17950, (2011)

Protein crystals usually grow at a preferable temperature which is however not known for a new protein. This paper reports a new approach for determination of favorable crystallization temperature, which can be adopted to facilitate the crystallization screen...

Using the water signal to detect invisible exchanging protons in the catalytic triad of a serine protease.

J. Biomol. NMR 50(4) , 299-314, (2011)

Chemical Exchange Saturation Transfer (CEST) is an MRI approach that can indirectly detect exchange broadened protons that are invisible in traditional NMR spectra. We modified the CEST pulse sequence for use on high-resolution spectrometers and developed a q...

Use of dynamic light scattering to determine second virial coefficient in a semidilute concentration regime.

Anal. Biochem. 411(2) , 292-6, (2011)

The present work discusses an alternative procedure to obtain static light scattering (SLS) parameters in a dilute and semidilute concentration regime from a dynamic light scattering (DLS) instrument that uses an avalanche photodiode (APD) for recording the s...

Thermodynamic analysis of alcohol effect on thermal stability of proteins.

J. Biosci. Bioeng. 111(2) , 198-203, (2011)

Thermal unfolding of ribonuclease A and α-chymotrypsinogen A was analyzed in various alcohol solutions of methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, 2-butanol, tert-butanol, trifluoroethanol, and glycerol. The change in thermal unfolding ratio with...

Hydration of proteins: excess partial volumes of water and proteins.

J. Phys. Chem. B 116(13) , 4098-105, (2012)

High precision densitometry was applied to study the hydration of proteins. The hydration process was analyzed by the simultaneous monitoring of the excess partial volumes of water and the proteins in the entire range of water content. Five unrelated proteins...

Rapid and highly sensitive protein extraction via cobalt oxide nanoparticle-based liquid-liquid microextraction coupled with MALDI mass spectrometry.

Analyst 137(4) , 890-5, (2012)

A new approach for rapid and highly sensitive protein extraction using cobalt oxide nanoparticles modified with cetyltrimethylammonium (Co(3)O(4)/CTA(+) NP) using nanoparticle-based liquid-liquid microextraction (NP-LLME) coupled with matrix-assisted laser de...

Complex interactions between molecular ions in solution and their effect on protein stability.

J. Am. Chem. Soc. 133(46) , 18713-8, (2011)

Protein stability in ionic solutions depends on the delicate balance between protein-ion and ion-ion interactions. For molecular ions containing multiple charged groups, the role of ion-ion interactions is particularly important. In this study, we show how th...