硫氧还蛋白 来源于大肠杆菌
硫氧还蛋白 来源于大肠杆菌结构式
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常用名 | 硫氧还蛋白 来源于大肠杆菌 | 英文名 | Thioredoxin, from Escherichia coli |
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| CAS号 | 52500-60-4 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | N/A | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Green tea polyphenol (-)-epigallocatechin-3-gallate triggered hepatotoxicity in mice: responses of major antioxidant enzymes and the Nrf2 rescue pathway.
Toxicol. Appl. Pharmacol. 283(1) , 65-74, (2015) (-)-Epigallocatechin-3-gallate (EGCG), a constituent of green tea, has been suggested to have numerous health-promoting effects. On the other hand, high-dose EGCG is able to evoke hepatotoxicity. In the present study, we elucidated the responses of hepatic ma... |
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Redox systems in Botrytis cinerea: impact on development and virulence.
Mol. Plant Microbe Interact. 27(8) , 858-74, (2014) The thioredoxin system is of great importance for maintenance of cellular redox homeostasis. Here, we show that it has a severe influence on virulence of Botrytis cinerea, demonstrating that redox processes are important for host-pathogen interactions in this... |
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Lactococcus lactis TrxD represents a subgroup of thioredoxins prevalent in Gram-positive bacteria containing WCXDC active site motifs.
Arch. Biochem. Biophys. 564 , 164-72, (2014) Three protein disulfide reductases of the thioredoxin superfamily from the industrially important Gram-positive Lactococcus lactis (LlTrxA, LlTrxD and LlNrdH) are compared to the "classical" thioredoxin from Escherichia coli (EcTrx1). LlTrxA resembles EcTrx1 ... |
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Redox metabolism in Trypanosoma cruzi: functional characterization of tryparedoxins revisited.
Free Radic. Biol. Med. 63 , 65-77, (2013) Tryparedoxins (TXNs) are multipurpose oxidoreductases from trypanosomatids that transfer reducing equivalents from trypanothione to various thiol proteins. In Trypanosoma cruzi, two genes coding for TXN-like proteins have been identified: TXNI, previously cha... |
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Adiponectin induces apoptosis in hepatocellular carcinoma through differential modulation of thioredoxin proteins.
Biochem. Pharmacol. 93(2) , 221-31, (2015) Adiponectin blocks hepatocellular carcinoma (HCC) progression by inducing cell apoptosis through the modulation of C-Jun N-terminal kinase and mammalian target of rapamycin. However, the precise upstream signaling pathways or molecules remain elusive. In the ... |
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Thioredoxin 1 is inactivated due to oxidation induced by peroxiredoxin under oxidative stress and reactivated by the glutaredoxin system.
J. Biol. Chem. 288(45) , 32241-7, (2013) The mammalian cytosolic thioredoxin system, comprising thioredoxin (Trx), Trx reductase, and NADPH, is the major protein-disulfide reductase of the cell and has numerous functions. Besides the active site thiols, human Trx1 contains three non-active site cyst... |
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Analysis of the expression and antioxidant activity of 2-Cys peroxiredoxin protein in Fasciola gigantica.
Exp. Parasitol. 140 , 24-32, (2014) 2-Cys peroxiredoxin (Prx) is the main antioxidant enzyme in Fasciola species for detoxifying hydrogen peroxide which is generated from the hosts' immune effector cells and the parasites' own metabolism. In this study, the recombinant Prx protein from Fasciola... |
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Renal redox dysregulation in AKI: application for oxidative stress marker of AKI.
Am. J. Physiol. Renal Physiol. 307(12) , F1342-51, (2014) Oxidative stress is a major determinant of acute kidney injury (AKI); however, the effects of an AKI on renal redox system are unclear, and few existing AKI markers are suitable for evaluating oxidative stress. We measured urinary levels of the redox-regulato... |
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The UDP-glucose pyrophosphorylase from Giardia lamblia is redox regulated and exhibits promiscuity to use galactose-1-phosphate.
Biochim. Biophys. Acta 1850(1) , 88-96, (2015) Giardia lamblia is a pathogen of humans and other vertebrates. The synthesis of glycogen and of structural oligo and polysaccharides critically determine the parasite's capacity for survival and pathogenicity. These characteristics establish that UDP-glucose ... |
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Use of a mouse in vitro fertilization model to understand the developmental origins of health and disease hypothesis.
Endocrinology 155(5) , 1956-69, (2014) The Developmental Origins of Health and Disease hypothesis holds that alterations to homeostasis during critical periods of development can predispose individuals to adult-onset chronic diseases such as diabetes and metabolic syndrome. It remains controversia... |