肝细胞生长因子乙酸盐
肝细胞生长因子乙酸盐结构式
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常用名 | 肝细胞生长因子乙酸盐 | 英文名 | Liver Cell Growth Factor acetate salt |
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| CAS号 | 72957-37-0 | 分子量 | 400.430 | |
| 密度 | 1.324 g/cmH3 | 沸点 | 831ºC at 760 mmHg | |
| 分子式 | C16H28N6O6 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 456.4ºC |
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Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species.
Endocrinology 156(4) , 1540-51, (2015) Na+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the first and rate-limiting step in the biosynthesis of the thyroid hormones. The expression and function of NIS in thyroid cells is mainly regulated by TSH and by the intracellular conc... |
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Expression analysis of stemness genes in a rat thyroid cell line FRTL5.
Exp. Clin. Endocrinol. Diabetes 123(1) , 48-54, (2015) Detection and analysis of a small subpopulation of cells such as stem cells or cancer stem cells are recognized to be a key technique in a recent regeneration and cancer science. However, in the thyroid, no marker that identifies stem cells has been establish... |
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The effect of topical tripeptide-copper complex on healing of ischemic open wounds.
Vet. Surg. 32(6) , 515-23, (2003) To evaluate the effects of topical glycyl-L-histidyl-L-lysine tripeptide-copper complex (TCC; Iamin 2% Gel; Procyte Corporation, Redmond, WA) on healing in ischemic open wounds.Experimental study.Twenty-four adult male Sprague-Dawley rats.Rats were divided in... |
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Acrolein sequestering ability of the endogenous tripeptide glycyl-histidyl-lysine (GHK): characterization of conjugation products by ESI-MSn and theoretical calculations.
J. Pharm. Biomed. Anal. 47(3) , 596-602, (2008) Acrolein (ACR) is a well-known carbonyl toxin produced by lipid peroxidation of polyunsaturated fatty acids, which is involved in several life-threatening pathologies such as Alzheimer disease, arteriosclerosis, diabetes, and nephropathy. The aim of this work... |
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Effects of copper tripeptide on the growth and expression of growth factors by normal and irradiated fibroblasts.
Arch. Facial Plast. Surg. 7(1) , 27-31, (2005) To evaluate the effects of copper tripeptide (GHK-Cu) on the growth and autocrine production of basic fibroblast growth factor, transforming growth factor beta1, and vascular endothelial growth factor by normal and irradiated fibroblasts in a serum-free in vi... |
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Copper.Lys-Gly-His-Lys mediated cleavage of tRNA(Phe): studies of reaction mechanism and cleavage specificity.
J. Inorg. Biochem. 103 , 871-875, (2009) The reactivity of [Cu2+.Lys-Gly-His-Lys-NH2]2+ and [Cu2+.Lys-Gly-His-Lys]+ toward tRNA(Phe) has been evaluated. The amidated and carboxylate forms of the copper peptides display complex binding behavior with strong and weak sites evident (K(D1)(app) approxima... |
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A therapeutic approach for diabetic wound healing using biotinylated GHK incorporated collagen matrices.
Life Sci. 80(4) , 275-84, (2007) Chronically elevated blood glucose levels result in reduced leukocyte function and cell malnutrition, which contribute to a high rate of wound infection and associated healing problems in diabetic patients. In the present study, the role of biotinylated GHK p... |
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Formation equilibria of nickel complexes with glycyl-histidyl-lysine and two synthetic analogues.
J. Inorg. Biochem. 98(1) , 153-60, (2004) Complex-formation equilibria between the Ni(II) ion and the natural tripeptide glycyl-L-histidyl-L-lysine have been investigated. Two synthetic analogues, where the histidine residue has been substituted with L-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-c... |
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The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health.
Oxid. Med. Cell. Longev. 2012 , 324832, (2012) Oxidative stress, disrupted copper homeostasis, and neuroinflammation due to overproduction of proinflammatory cytokines are considered leading causative factors in development of age-associated neurodegenerative conditions. Recently, a new mechanism of aging... |
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Effects of topical copper tripeptide complex on wound healing in an irradiated rat model.
Otolaryngol. Head Neck Surg. 149(3) , 384-9, (2013) To evaluate clinical and immunohistopathological effects of topical glycyl-histidyl-lysine-copper (GHK-Cu) on in vivo irradiated rat wounds.Animal model.Academic institution.After dorsal irradiation and a 28-day recovery period, 2 × 8 cm cranially based dorsa... |