2,4,6-三叔丁基苯酚
2,4,6-三叔丁基苯酚结构式
|
常用名 | 2,4,6-三叔丁基苯酚 | 英文名 | 2,4,6-Tri-tert-butylphenol |
|---|---|---|---|---|
| CAS号 | 732-26-3 | 分子量 | 262.430 | |
| 密度 | 0.9±0.1 g/cm3 | 沸点 | 278.0±0.0 °C at 760 mmHg | |
| 分子式 | C18H30O | 熔点 | 125-130 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 129.3±8.4 °C | |
| 符号 |
GHS07, GHS09 |
信号词 | Warning |
|
In-vivo passive sampling to measure elimination kinetics in bioaccumulation tests.
Chemosphere 88(1) , 62-8, (2012) The application of in-tissue passive sampling to quantify chemical kinetics in fish bioconcentration experiments was investigated. A passive sampler consisting of an acupuncture needle covered with a PDMS tube was developed together with a method for its depl... |
|
|
Radical production and cytotoxic activity of tert-butyl-substituted phenols.
In Vitr. Mol. Toxicol. 14(1) , 53-63, (2001) 2,4,6-Tri-tert-butylphenol (TBP)-related compounds are used for stabilizing plastics by making them resistant to oxidation. However, the cytotoxic activity of these compounds has not yet been established. TBP produced phenoxyl radicals at pH >or= 9.0 and 2,4-... |
|
|
The role of low levels of water in the electrochemical oxidation of α-tocopherol (vitamin E) and other phenols in acetonitrile.
Phys. Chem. Chem. Phys. 13(28) , 12745-54, (2011) The phenol, α-tocopherol, can be electrochemically oxidised in a -2e(-)/-H(+) process to form a diamagnetic cation that is long-lived in dry organic solvents such as acetonitrile and dichloromethane, but in the presence of water quickly reacts to form a hemik... |
|
|
Chronic toxicity of 2,4,6-tri-tert-butylphenol in rats.
J. Toxicol. Sci. 16(4) , 167-79, (1991) In order to study the chronic toxicity of 2, 4, 6-tri-tert-butylphenol (TTBP), groups of 40 Slc: Wistar rats of either sex were fed diet containing 0, 30, 100, 300 or 1000 ppm of TTBP for up to 24 months. Hematological, biochemical and histopathological exami... |
|
|
Polyunsaturated fatty acid alkoxyl radicals exist as carbon-centered epoxyallylic radicals: a key step in hydroperoxide-amplified lipid peroxidation.
Chem. Res. Toxicol. 6(4) , 413-6, (1993) 13-Hydroperoxyoctadeca-9,11,15-trienoic acid was reacted with a catalytic amount of 5,10,15,20-tetraphenyl-21H,23H-porphyrin iron(III) chloride in dichloromethane containing 2,4,6-tri-tert-butylphenol. The principal products were identified as 13-oxooctadeca-... |
|
|
Hydrogen atom abstraction by a high-valent manganese(V)-oxo corrolazine.
Inorg. Chem. 45(13) , 5119-25, (2006) High-valent metal-oxo complexes are postulated as key intermediates for a wide range of enzymatic and synthetic processes. To gain an understanding of these processes, the reactivity of an isolated, well-characterized Mn(V)-oxo complex, (TBP8Cz)MnVO (1), (TBP... |
|
|
C-H bond activation by a ferric methoxide complex: modeling the rate-determining step in the mechanism of lipoxygenase.
J. Am. Chem. Soc. 124(1) , 83-96, (2002) Lipoxygenases are mononuclear non-heme iron enzymes that regio- and stereospecifcally convert 1,4-pentadiene subunit-containing fatty acids into alkyl peroxides. The rate-determining step is generally accepted to be hydrogen atom abstraction from the pentadie... |
|
|
Mechanisms of cytotoxicity of 2- or 2,6-di-tert-butylphenols and 2-methoxyphenols in terms of inhibition rate constant and a theoretical parameter.
Chemosphere 74(5) , 626-32, (2009) To clarify the mechanism of phenol toxicity, the radical-scavenging activity of 2- or 2,6-di-tert-butyl- and 2-methoxy-substituted phenols was investigated by combining two distinct approaches: first, the induction period method for methacrylate polymerizatio... |
|
|
Spectroscopic observation of iodosylarene metalloporphyrin adducts and manganese(V)-oxo porphyrin species in a cytochrome P450 analogue.
Nat. Commun. 3 , 1190, (2012) Different metalloporphyrin model compounds have been synthesized to study the mechanisms of cytochrome P450s with various terminal oxidants, and numerous intermediates have been reported. However, the detailed mechanism of the oxygen atom transfer from iodosy... |
|
|
Metabolic studies in the rat with 2,4,6-tri-t-butylphenol: a haemorrhagic antioxidant structurally related to butylated hydroxytoluene.
Xenobiotica 13(5) , 319-26, (1983) Single oral doses of the haemorrhagic antioxidant 2,4,6-tri-t-butylphenol (260 mg/kg) were well absorbed in the rat. Peak blood levels of this compound were reached in 15-60 min. The blood elimination half-lives were 18.2 min for the alpha-phase and 11.8 h fo... |