酒石酸麦角胺
一般危化品
酒石酸麦角胺结构式
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常用名 | 酒石酸麦角胺 | 英文名 | ERGOTAMINE TARTRATE |
|---|---|---|---|---|
| CAS号 | 379-79-3 | 分子量 | 731.748 | |
| 密度 | 1.47g/cm3 | 沸点 | 914.5ºC at 760mmHg | |
| 分子式 | C37H41N5O11 | 熔点 | -195ºC (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS06, GHS08 |
信号词 | Danger |
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GR-127935-sensitive mechanism mediating hypotension in anesthetized rats: are 5-HT5B receptors involved?
J. Cardiovasc. Pharmacol. 65(4) , 335-41, (2015) The 5-HT1B/1D receptor antagonist, GR-127935, inhibits hypotensive responses produced by the 5-HT1A, 5-HT1B/1D and 5-HT7 receptor agonist, and 5-HT5A/5B receptor ligand, 5-carboxamidotryptamine (5-CT), in rats. This work further characterized the above mechan... |
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Cell-free microfluidic determination of P-glycoprotein interactions with substrates and inhibitors.
Pharm. Res. 31(12) , 3415-25, (2014) The membrane protein P-glycoprotein (P-gp) plays key roles in the oral bioavailability of drugs, their blood brain barrier passage as well as in multidrug resistance. For new drug candidates it is mandatory to study their interaction with P-gp, according to F... |
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Links between Genetic Groups, Indole Alkaloid Profiles and Ecology within the Grass-Parasitic Claviceps purpurea Species Complex.
Toxins (Basel.) 7 , 1431-56, (2015) The grass parasitic fungus Claviceps purpurea sensu lato produces sclerotia with toxic indole alkaloids. It constitutes several genetic groups with divergent habitat preferences that recently were delimited into separate proposed species. We aimed to 1) analy... |
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Structural basis for molecular recognition at serotonin receptors.
Science 340(6132) , 610-4, (2013) Serotonin or 5-hydroxytryptamine (5-HT) regulates a wide spectrum of human physiology through the 5-HT receptor family. We report the crystal structures of the human 5-HT1B G protein-coupled receptor bound to the agonist antimigraine medications ergotamine an... |
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What happens to the old headache medicines?
Headache 52(4) , 701-6, (2012) Old headache medicines never die; they either fade away or come back in disguise. The disguise is often a new route of administration, which may work better, faster, more completely, with fewer adverse events, and/or have certain other advantages. The clinica... |
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Headache currents commentary.
Headache 52(4) , 715, (2012) What Happens to the Old Headache Medicines? Rapoport AM, MD. Old headache medicines never die; they either fade away or come back in disguise. The disguise is often a new route of administration, which may work better, faster, more completely, with fewer adve... |
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Dihydroergotamine, ergotamine, methysergide and sumatriptan - basic science in relation to migraine treatment.
Headache 52(4) , 707-14, (2012) The 5-hydroxytryptamine (5-HT) receptor family mediates the effects of several drugs highly effective in migraine primarily by activating 5-HT(1B) , 5-HT(1D) , and 5-HT(1F) receptors. Ergotamine, dihydroergotamine, and methysergide, as well as the "triptan" s... |
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Management of cluster headache.
CNS Drugs 26(7) , 571-80, (2012) The prevalence of cluster headache is 0.1% and cluster headache is often not diagnosed or misdiagnosed as migraine or sinusitis. In cluster headache there is often a considerable diagnostic delay - an average of 7 years in a population-based survey. Cluster h... |
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Ergotamine-induced pleural and pericardial effusion successfully treated with colchicine.
Acta Clin. Belg. 68(2) , 113-5, (2013) A 83-year-old woman was admitted to hospital with chest pain, fever, dry cough and palpitations. Chest X-ray revealed a pleural effusion, assumed to be caused by cardiac failure and respiratory infection. Despite treatment with antibiotics and diuretics, the ... |
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Structural features for functional selectivity at serotonin receptors.
Science 340(6132) , 615-9, (2013) Drugs active at G protein-coupled receptors (GPCRs) can differentially modulate either canonical or noncanonical signaling pathways via a phenomenon known as functional selectivity or biased signaling. We report biochemical studies showing that the hallucinog... |