尼可刹米
尼可刹米结构式
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常用名 | 尼可刹米 | 英文名 | Nikethamide |
|---|---|---|---|---|
| CAS号 | 59-26-7 | 分子量 | 178.231 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 298.0±0.0 °C at 760 mmHg | |
| 分子式 | C10H14N2O | 熔点 | 23 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 141.1±20.4 °C | |
| 符号 |
GHS06 |
信号词 | Danger |
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High throughput quantification of prohibited substances in plasma using thin film solid phase microextraction.
J. Chromatogr. A. 1374 , 40-9, (2014) Simple, fast and efficient sample preparation approaches that allow high-throughput isolation of various compounds from complex matrices are highly desired in bioanalysis. Particularly sought are methods that can, without sacrificing time, easily remove matri... |
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Screening method for stimulants in urine by UHPLC-MS/MS: identification of isomeric compounds.
Drug Test. Anal. 7 , 819-30, (2015) A fast screening method for the detection of more than 60 stimulants in urine was developed. The method consisted of a dilution of the urine (1:5 v/v) and analysis by ultra high performance liquid chromatography coupled to tandem mass spectrometry, using a C1... |
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Mechanistic studies on hydrotropic solubilization of nifedipine in nicotinamide solution.
Chem. Pharm. Bull. 46(1) , 125-30, (1998) Nicotinamide is a hydrotropic agent that has been demonstrated to solubilize a wide variety of drugs through complexation. Past investigations on the potential interaction of nicotinamide with a solubilized drug have inadequately focused on aliphatic hydrotro... |
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[Disturbed functioning of enzyme systems of microsomal oxidation, glucuro-, and glutathione conjugation of xenobiotics in the liver of rats intoxicated by deoxycholate and their correction].
Biull. Eksp. Biol. Med. 129(3) , 297-301, (2000)
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[Disturbed functioning of enzyme systems of the microsomal oxidation, glucuro- and glutathione conjugation of xenobiotics in the liver of rats intoxicated by deoxycholate and their correction].
Biull. Eksp. Biol. Med. 129(1) , 56-60, (2000)
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[Inhibition of the antioxidant protection, microsomal oxidation, and xenobiotic glucuroconjugation in rats with cholestasis and their regulation].
Biull. Eksp. Biol. Med. 127(2) , 194-7, (1999)
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Effects of ethylene glycol-based graft, star-shaped, and dendritic polymers on solubilization and controlled release of paclitaxel.
J. Control. Release 93(2) , 121-7, (2003) New methods and pharmaceutical compositions were developed to increase the aqueous solubility of paclitaxel (PTX), a poorly water-soluble drug. Graft and star-shaped graft polymers consisting of poly(ethylene glycol) (PEG400) graft chains increased the PTX so... |
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Paclitaxel-loaded microparticles and implants for the treatment of brain cancer: preparation and physicochemical characterization.
Int. J. Pharm. 314(2) , 127-36, (2006) The aim of this study was to prepare different types of paclitaxel-loaded, PLGA-based microparticles and lipidic implants, which can directly be injected into the brain tissue. Releasing the drug in a time-controlled manner over several weeks, these systems a... |
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Sedative, hypnotic and anticonvulsant activities of the ethanol fraction from Rhizoma Pinelliae Praeparatum
J. Ethnopharmacol. 135(2) , 325-9, (2011) Pinelliae had been used for treatment of insomnia since ancients in Chinese. Sedative, hypnotic and anticonvulsant effects of ethanol fraction of Rhizoma Pinelliae Praeparatum were evaluated. The extract demonstrated sedative, hypnotic and anticonvulsant acti... |
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Determination of stimulants using gas chromatography/high-resolution time-of-flight mass spectrometry and a soft ionization source.
Rapid Commun. Mass Spectrom. 26(23) , 2714-24, (2012) The aim of this study was to investigate the mass spectral fragmentation of a small set of stimulants in a high-resolution time-of-flight mass spectrometer equipped with a soft ionization source using vacuum ultraviolet (VUV) photons emitted from different pl... |