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苯乙酸

一般危化品
苯乙酸结构式
苯乙酸结构式
常用名 苯乙酸 英文名 Phenylacetic acid
CAS号 103-82-2 分子量 136.148
密度 1.2±0.1 g/cm3 沸点 265.5±0.0 °C at 760 mmHg
分子式 C8H8O2 熔点 76-78 °C(lit.)
MSDS 中文版 美版 闪点 156.2±13.9 °C
符号 GHS07
GHS07
信号词 Warning

25-O-acetyl-23,24-dihydro-cucurbitacin F induces cell cycle G2/M arrest and apoptosis in human soft tissue sarcoma cells.

J. Ethnopharmacol. 164 , 265-72, (2015)

Quisqualis indica is used in traditional Chinese medicine to treat cancer and related syndromes and also known for its anthelminthic effects.Soft tissue sarcomas represent a rare group of malignant tumors that frequently exhibit chemotherapeutic resistance an...

Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility.

J. Virol. 89(8) , 4636-44, (2015)

DNA polymerases of the Herpesviridae and bacteriophage RB69 belong to the α-like DNA polymerase family. In spite of similarities in structure and function, the RB69 enzyme is relatively resistant to foscarnet, requiring the mutation V478W in helix N to promot...

Identification and characterization of epithelial cells derived from human ovarian follicular fluid.

Stem Cell Res. Ther. 6 , 13, (2015)

Follicular fluid is important for follicular development and oocyte maturation. Evidence suggests that follicular fluid is not only rich in proteins but cells. Besides oocytes, the follicular fluid contains granulosa, thecal, and ovarian surface epithelial ce...

Matrix stiffening and β1 integrin drive subtype-specific fibroblast accumulation in lung cancer.

Mol. Cancer Res. 13(1) , 161-73, (2015)

The crucial role of tumor-associated fibroblasts (TAF) in cancer progression is now clear in non-small cell lung cancer (NSCLC). However, therapies against TAFs are limited due to a lack of understanding in the subtype-specific mechanisms underlying their acc...

The HMGB1 protein sensitizes colon carcinoma cells to cell death triggered by pro-apoptotic agents.

Int. J. Oncol. 46(2) , 667-76, (2014)

The HMGB1 protein has multiple functions in tumor biology and can act both as a transcription factor and as a cytokine. HMGB1 is released during cell death, and in our previous studies we demonstrated that HMGB1 induces a distinct, necrosis-like cell death in...

Mechanical stimulation of human tendon stem/progenitor cells results in upregulation of matrix proteins, integrins and MMPs, and activation of p38 and ERK1/2 kinases.

BMC Mol. Biol. 16 , 6, (2015)

Tendons are dense connective tissues subjected periodically to mechanical stress upon which complex responsive mechanisms are activated. These mechanisms affect not only the development of these tissues but also their healing. Despite of the acknowledged impo...

KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction.

EMBO J. 34(4) , 448-65, (2015)

Paradoxically, the thymidine kinase (TK) encoded by Kaposi sarcoma-associated herpesvirus (KSHV) is an extremely inefficient nucleoside kinase, when compared to TKs from related herpesviruses. We now show that KSHV-TK, in contrast to HSV1-TK, associates with ...

Is sexual reproduction of high-mountain plants endangered by heat?

Oecologia 177(4) , 1195-210, (2015)

Strong solar irradiation in combination with still air and dry soil can cause prostrate high-mountain plants to heat up considerably and ultimately suffer heat damage. Such heat damage has been repeatedly shown for vegetative structures, but not for reproduct...

Pharmacological characterization of [3H]VUF11211, a novel radiolabeled small-molecule inverse agonist for the chemokine receptor CXCR3.

Mol. Pharmacol. 87(4) , 639-48, (2015)

Chemokine receptor CXCR3 has attracted much attention, as it is thought to be associated with a wide range of immune-related diseases. As such, several small molecules with different chemical structures targeting CXCR3 have been discovered. Despite limited cl...

Septins arrange F-actin-containing fibers on the Chlamydia trachomatis inclusion and are required for normal release of the inclusion by extrusion.

MBio 5(5) , e01802-14, (2014)

Chlamydia trachomatis is an obligate intracellular human pathogen that grows inside a membranous, cytosolic vacuole termed an inclusion. Septins are a group of 13 GTP-binding proteins that assemble into oligomeric complexes and that can form higher-order fila...