N-(4-氨基丁基)-2-萘磺酰胺盐酸盐
N-(4-氨基丁基)-2-萘磺酰胺盐酸盐结构式
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常用名 | N-(4-氨基丁基)-2-萘磺酰胺盐酸盐 | 英文名 | N-(4-Aminobutyl)-2-naphthalenesulfonamide Hydrochloride |
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| CAS号 | 89108-46-3 | 分子量 | 314.83100 | |
| 密度 | N/A | 沸点 | 474.7ºC at 760 mmHg | |
| 分子式 | C14H19ClN2O2S | 熔点 | 181-182°C | |
| MSDS | 中文版 美版 | 闪点 | 240.9ºC |
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Calmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production.
Sci. Signal. 7(337) , ra74, (2014) Precise regulation of the kinetics and magnitude of Ca(2+) signaling enables this signal to mediate diverse responses, such as cell migration, differentiation, vesicular trafficking, and cell death. We showed that the Ca(2+)-binding protein calmodulin (CaM) a... |
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N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation.
Proc. Natl. Acad. Sci. U. S. A. 78 , 4354, (1981) N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) and its derivatives are putative calmodulin antagonists that bind to calmodulin and inhibit Ca2+/calmodulin-regulated enzyme activities. Autoradiographic studies using tritiated W-7 showed that this com... |
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A role for calcium-calmodulin in regulating nitric oxide production during skeletal muscle satellite cell activation.
Am. J. Physiol. Cell Physiol. 296 , C922-9, (2009) When skeletal muscle is stretched or injured, myogenic satellite cells are activated to enter the cell cycle. This process depends on nitric oxide (NO) production by NO synthase (NOS), matrix metalloproteinase activation, release of hepatocyte growth factor (... |