N-(4-Aminobutyl)-2-naphthalenesulfonamide Hydrochloride
N-(4-Aminobutyl)-2-naphthalenesulfonamide Hydrochloride structure
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Common Name | N-(4-Aminobutyl)-2-naphthalenesulfonamide Hydrochloride | ||
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| CAS Number | 89108-46-3 | Molecular Weight | 314.83100 | |
| Density | N/A | Boiling Point | 474.7ºC at 760 mmHg | |
| Molecular Formula | C14H19ClN2O2S | Melting Point | 181-182°C | |
| MSDS | Chinese USA | Flash Point | 240.9ºC | |
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Calmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production.
Sci. Signal. 7(337) , ra74, (2014) Precise regulation of the kinetics and magnitude of Ca(2+) signaling enables this signal to mediate diverse responses, such as cell migration, differentiation, vesicular trafficking, and cell death. We showed that the Ca(2+)-binding protein calmodulin (CaM) a... |
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N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation.
Proc. Natl. Acad. Sci. U. S. A. 78 , 4354, (1981) N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) and its derivatives are putative calmodulin antagonists that bind to calmodulin and inhibit Ca2+/calmodulin-regulated enzyme activities. Autoradiographic studies using tritiated W-7 showed that this com... |
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A role for calcium-calmodulin in regulating nitric oxide production during skeletal muscle satellite cell activation.
Am. J. Physiol. Cell Physiol. 296 , C922-9, (2009) When skeletal muscle is stretched or injured, myogenic satellite cells are activated to enter the cell cycle. This process depends on nitric oxide (NO) production by NO synthase (NOS), matrix metalloproteinase activation, release of hepatocyte growth factor (... |