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Ro04-6790,5-HT6拮抗剂

Ro04-6790,5-HT6拮抗剂结构式
Ro04-6790,5-HT6拮抗剂结构式
品牌特惠专场
常用名 Ro04-6790,5-HT6拮抗剂 英文名 Ro 04-6790
CAS号 202466-68-0 分子量 308.359
密度 1.5±0.1 g/cm3 沸点 595.8±60.0 °C at 760 mmHg
分子式 C12H16N6O2S 熔点 N/A
MSDS 美版 闪点 314.1±32.9 °C

Characterization of Ro 04-6790 and Ro 63-0563: potent and selective antagonists at human and rat 5-HT6 receptors.

Br. J. Pharmacol. 124 , 556-562, (1998)

1. This study describes the in vitro characterization of two potent and selective 5-HT6 receptor antagonists at the rat and human recombinant 5-HT6 receptor. 2. In binding assays with [3H]-LSD, 4-amino-N-(2,6 bis-methylamino-pyrimidin-4-yl)-benzene sulphonami...

Investigation of stretching behaviour induced by the selective 5-HT6 receptor antagonist, Ro 04-6790, in rats.

Br. J. Pharmacol. 126 , 1537-1542, (1999)

1. The present study examined the effects of the selective 5-HT6 receptor antagonist 4-amino-N-(2, 6 bis-methylamino-pyrimidin-4-yl)-benzene sulphonamide (Ro 04-6790) on locomotor activity and unconditioned behaviour in male Sprague Dawley rats (230-300 g). 2...