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蛋白酶激活的受体-2,酰胺

蛋白酶激活的受体-2,酰胺结构式
蛋白酶激活的受体-2,酰胺结构式
品牌特惠专场
常用名 蛋白酶激活的受体-2,酰胺 英文名 SLIGKV-NH2
CAS号 190383-13-2 分子量 614.77800
密度 N/A 沸点 N/A
分子式 C28H54N8O7 熔点 N/A
MSDS 中文版 美版 闪点 N/A

The effect of kinin B1 receptor on chronic itching sensitization.

Mol. Pain 11 , 70, (2015)

Altered kallikrein-related peptidase activity and bradykinin are associated with skin disorders in humans and mice under chronic inflammation conditions. The bradykinin B1 receptor (B1R), also known as one of the G-protein-coupled receptor family and usually ...

Heparin inhibits melanosome uptake and inflammatory response coupled with phagocytosis through blocking PI3k/Akt and MEK/ERK signaling pathways in human epidermal keratinocytes.

Pigment Cell Melanoma Res. 27(6) , 1063-74, (2014)

To gain insight for the role of mast cell-produced heparin in the regulation of epidermal homeostasis and skin pigmentation, we have investigated the effect of heparin on melanosome uptake and proinflammatory responses in normal human epidermal keratinocytes ...

Activation of TRPV1 mediates thymic stromal lymphopoietin release via the Ca2+/NFAT pathway in airway epithelial cells.

FEBS Lett. 588(17) , 3047-54, (2014)

The airway epithelium is exposed to a range of irritants in the environment that are known to trigger inflammatory response such as asthma. Transient receptor potential vanilloid 1 (TRPV1) is a Ca(2+)-permeable cation channel critical for detecting noxious st...

Intestinal protease-activated receptor-2 and fecal serine protease activity are increased in canine inflammatory bowel disease and may contribute to intestinal cytokine expression.

J. Vet. Med. Sci. 76(8) , 1119-27, (2014)

Serine proteases elicit cellular responses via protease-activated receptor-2 (PAR-2) which is known to regulate inflammation and the immune response. Although the gastrointestinal tract is exposed to large amounts of proteolytic enzymes, the role of PAR-2 in ...

Thrombin Augments LPS-Induced Human Endometrial Endothelial Cell Inflammation via PAR1 Activation.

Am. J. Reprod. Immunol. 76 , 29-37, (2016)

Risk factors for preterm birth include placental abruption, giving rise to excessive decidual thrombin, and intrauterine bacterial infection. Human endometrial endothelial cells (HEECs) express Toll-like receptors (TLRs), and infection-derived agonists trigge...