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罗红霉素钙盐

罗红霉素钙盐结构式
罗红霉素钙盐结构式
品牌特惠专场
常用名 罗红霉素钙盐 英文名 Ionomycin calcium salt
CAS号 56092-82-1 分子量 747.067
密度 N/A 沸点 817.2ºC at 760mmHg
分子式 C41H70CaO9 熔点 205-206ºC
MSDS 中文版 美版 闪点 235.2ºC
符号 GHS07
GHS07
信号词 Warning

P2X receptors regulate adenosine diphosphate release from hepatic cells.

Purinergic Signal. 10(4) , 587-93, (2014)

Extracellular nucleotides act as paracrine regulators of cellular signaling and metabolic pathways. Adenosine polyphosphate (adenosine triphosphate (ATP) and adenosine diphosphate (ADP)) release and metabolism by human hepatic carcinoma cells was therefore ev...

Myeloid Sirtuin 2 Expression Does Not Impact Long-Term Mycobacterium tuberculosis Control.

PLoS ONE 10 , e0131904, (2015)

Sirtuins (Sirts) regulate several cellular mechanisms through deacetylation of several transcription factors and enzymes. Recently, Sirt2 was shown to prevent the development of inflammatory processes and its expression favors acute Listeria monocytogenes inf...

Dendritic cell-secreted lipocalin2 induces CD8+ T-cell apoptosis, contributes to T-cell priming and leads to a TH1 phenotype.

PLoS ONE 9(7) , e101881, (2014)

Lipocalin 2 (LCN2), which is highly expressed by dendritic cells (DCs) when treated with dexamethasone (Dex) and lipopolysaccharide (LPS), plays a key role in the defence against bacteria and is also involved in the autocrine apoptosis of T-cells. However, th...

Trabecular bone loss in collagen antibody-induced arthritis.

Arthritis. Res. Ther. 17 , 189, (2015)

Postmenopausal women with rheumatoid arthritis (RA) have increased risk of developing osteoporosis due to chronic inflammation and estrogen deprivation. Collagen antibody-induced arthritis (CAIA), an experimental polyarthritis model representing the effector ...

Regulatory T cell levels and cytokine production in active non-infectious uveitis: in-vitro effects of pharmacological treatment.

Clin. Exp. Immunol. 179(3) , 529-38, (2015)

The aim of this study was to quantify the proportion of regulatory T cells (Treg ) and cytokine expression by peripheral blood mononuclear cells (PBMCs) in patients with active non-infectious uveitis, and to evaluate the effect of in-vitro treatment with infl...

IL-33/ST2 axis controls Th2/IL-31 and Th17 immune response in allergic airway diseases.

Immunobiology 220 , 954-63, (2015)

IL-33 targeting ST2 receptor (T1/ST2), expressed on Th2 cell surface, regulates the production of cytokines like IL-17A and IL-31. We studied the role of IL-33/ST2 axis in IL-31 and IL-17A production in patients with allergic rhinitis (AR) and with concomitan...

Immature dendritic cells convert anergic nonregulatory T cells into Foxp3- IL-10+ regulatory T cells by engaging CD28 and CTLA-4.

Eur. J. Immunol. 45(2) , 480-91, (2015)

Anergic T cells can survive for long time periods passively in a hyporesponsive state without obvious active functions. Thus, the immunological reason for their maintenance is unclear. Here, we induced peptide-specific anergy in T cells from mice by coculturi...

Th17/Treg balance in children with obstructive sleep apnea syndrome and the relationship with allergic rhinitis.

Int. J. Pediatr. Otorhinolaryngol. 79 , 1448-54, (2015)

This study aims to explore the role of the Th17 to Treg cell ratio in children with OSA and its relationship with allergic rhinitis.The study included 127 children diagnosed with OSA by polysomnography (PSG) testing and 29 children without OSA. The 127 childr...

Regulation of Angiogenic Functions by Angiopoietins through Calcium-Dependent Signaling Pathways.

Biomed Res. Int. 2015 , 965271, (2015)

Angiopoietins are vascular factors essential for blood vessel assembly and correct organization and maturation. This study describes a novel calcium-dependent machinery activated through Angiopoietin-1/2-Tie receptor system in HUVECs monolayer. Both cytokines...

Attenuation of immune-mediated influenza pneumonia by targeting the inducible co-stimulator (ICOS) molecule on T cells.

PLoS ONE 9(7) , e100970, (2014)

Inducible Co-stimulator (ICOS) plays a critical role in mediating T cell differentiation and function and is considered a key player in balancing T effector and T regulatory (Treg) cell responses. Here we show that activation of the ICOS signalling pathway du...