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6-[(7-硝基-2,1,3-苯并恶二唑-4-基)氨基]己酸

6-[(7-硝基-2,1,3-苯并恶二唑-4-基)氨基]己酸结构式
6-[(7-硝基-2,1,3-苯并恶二唑-4-基)氨基]己酸结构式
品牌特惠专场
常用名 6-[(7-硝基-2,1,3-苯并恶二唑-4-基)氨基]己酸 英文名 6-((7-NITROBENZO[C][1,2,5]OXADIAZOL-4-YL)AMINO)HEXANOIC ACID
CAS号 88235-25-0 分子量 294.26300
密度 1.462 沸点 559.4ºC at 760 mmHg
分子式 C12H14N4O5 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS06
GHS06
信号词 Danger

A cyclic GB virus C derived peptide with anti-HIV-1 activity targets the fusion peptide of HIV-1

Eur. J. Med. Chem. 86 , 589-604, (2014)

The development of peptide fusion inhibitors based on short synthetic peptides represents a promising option in the fight against HIV-1 infection, especially in individuals infected with multiresistant HIV-1 strains. GBV-C has the beneficial effect of retardi...

Probing the ligand binding sites of fatty acid and sterol carrier proteins: effects of ethanol.

Biochemistry 34 , 11919, (1995)

Direct effects of ethanol on the interaction of cytosolic lipid transfer proteins with ligands are not known. In this study, recombinant liver fatty acid binding protein (L-FABP) and sterol carrier protein-2 (SCP-2) were used in conjunction with a series of f...

Multidrug resistance protein 1 regulates lipid asymmetry in erythrocyte membranes.

Biochem. J. 350 Pt 2 , 531-5, (2000)

The role of multidrug resistance protein 1 (MRP1) in the maintenance of transbilayer lipid asymmetry in the erythrocyte membrane was investigated. The transbilayer distribution of endogenous phospholipids and [(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]hexanoyl...

Contribution of hydrogen bonding to lipid-lipid interactions in membranes and the role of lipid order: effects of cholesterol, increased phospholipid unsaturation, and ethanol.

Biochemistry 32(14) , 3714-21, (1993)

It is proposed that increased phospholipid unsaturation in membranes and perturbation by agents such as ethanol weaken interlipid hydrogen bonding involving water and that the process is independent of effects on lipid order. To investigate this, the rates of...

Time-resolved fluorescence of nitrobenzoxadiazole-aminohexanoic acid: effect of intermolecular hydrogen-bonding on non-radiative decay.

Photochem. Photobiol. 54(3) , 361-5, (1991)

The fluorescence kinetics of the nitrobenzoxadiazole (NBD) chromophore were studied at low concentrations in solvents with varying polarity and hydrogen-bonding donor strength. The emission decay was essentially single exponential in all solvents studied. Whi...

The internalization of a short acyl chain analogue of ganglioside GM1 in polarized neurons.

J. Cell Sci. 109 ( Pt 8) , 2111-9, (1996)

In order to study the endocytosis of membrane lipids during the development of neuronal polarity, we examined the internalization of a short acyl chain fluorescent derivative of ganglioside GM1, N-(6-(4-nitrobenz-2-oxa-1,3-diazole-7-yl)-aminohexanoyl)-GM1 (C6...

Role of prothrombin fragment 1 in the pathway of regulatory exosite I formation during conversion of human prothrombin to thrombin.

J. Biol. Chem. 278(45) , 44489-95, (2003)

Prothrombin (Pro) activation by factor Xa generates the thrombin catalytic site and exosites I and II. The role of fragment 1 (F1) in the pathway of exosite I expression during Pro activation was characterized in equilibrium binding studies using hirudin(54-6...

Synthesis and characterization of fluorescent neutral lipid analogs containing N-(7-nitro-2,1,3-benzoxadiazol-4-yl)-aminohexanoic acid.

Chem. Phys. Lipids 66(3) , 171-80, (1993)

The synthesis, identification and characterization of neutral lipid analogs containing N-(7-nitro-2,1,3-benzoxadiazoi-4-yl)-aminocaproic acid are reported. The acyl-imidazole derivative of the fluorescent fatty acid was used to esterify L-alpha-glycerophospho...