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2-氨基-5-溴-3-硝基吡啶

2-氨基-5-溴-3-硝基吡啶结构式
2-氨基-5-溴-3-硝基吡啶结构式
品牌特惠专场
常用名 2-氨基-5-溴-3-硝基吡啶 英文名 5-Brom-3-nitropyridin-2-amin
CAS号 6945-68-2 分子量 218.01
密度 1.9±0.1 g/cm3 沸点 302.9±37.0 °C at 760 mmHg
分子式 C5H4BrN3O2 熔点 205-208 °C(lit.)
MSDS 中文版 美版 闪点 137.0±26.5 °C
符号 GHS07
GHS07
信号词 Warning

Discovery of 6-({4-[2-(4-tert-butylphenyl)-1H-benzimidazol-4-yl]piperazin-1-yl}methyl)quinoxaline (WAY-207024): an orally active antagonist of the gonadotropin releasing hormone receptor (GnRH-R).

J. Med. Chem. 52(7) , 2148-52, (2009)

A potent, highly insoluble, GnRH antagonist with a 2-phenyl-4-piperazinylbenzimidazole template and a quinoxaline-2,3-dione pharmacophore was modified to maintain GnRH antagonist activity and improve in vitro pharmaceutical properties. Structural changes to t...

2, 3-Diaminopyridine. Fox BA and Threlfall TL.

Organic Synth. , 34-34, (1973)