10-[2-(1-甲基-2-哌啶基)乙基]-2-(甲基亚磺酰基)-10h-苯并噻嗪
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10-[2-(1-甲基-2-哌啶基)乙基]-2-(甲基亚磺酰基)-10h-苯并噻嗪结构式
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常用名 | 10-[2-(1-甲基-2-哌啶基)乙基]-2-(甲基亚磺酰基)-10h-苯并噻嗪 | 英文名 | Mesoridazine besylate |
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| CAS号 | 32672-69-8 | 分子量 | 544.74900 | |
| 密度 | N/A | 沸点 | 570.5ºC at 760mmHg | |
| 分子式 | C27H32N2O4S3 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 298.9ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Thioridazine steady-state plasma concentrations are influenced by tobacco smoking and CYP2D6, but not by the CYP2C9 genotype.
Eur. J. Clin. Pharmacol. 59 , 45-50, (2003) Approximately 7% of Caucasians have genetically impaired activity of the cytochrome P450 enzyme CYP2D6 and are classified as poor metabolizers (PM). The disposition of thioridazine has been related to the CYP2D6 phenotype. The present study aimed to evaluate ... |
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Inverse agonist actions of typical and atypical antipsychotic drugs at the human 5-hydroxytryptamine(2C) receptor.
J. Pharmacol. Exp. Ther. 299 , 83-89, (2001) Atypical antipsychotic drugs, which are distinguished from typical antipsychotic drugs by a lower incidence of extra-pyramidal side effects and less propensity to elevate serum prolactin levels (e.g., clozapine, olanzapine, risperidone, quetiapine, ziprasidon... |
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