橙皮苷甲基查尔酮
橙皮苷甲基查尔酮结构式
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常用名 | 橙皮苷甲基查尔酮 | 英文名 | Hesperidin methylchalcone |
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| CAS号 | 24292-52-2 | 分子量 | 624.587 | |
| 密度 | 1.6±0.1 g/cm3 | 沸点 | 953.0±65.0 °C at 760 mmHg | |
| 分子式 | C29H36O15 | 熔点 | 120 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 309.5±27.8 °C |
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Assessment of the antineoplastic potential of chalcones in animal models.
Curr. Med. Chem. 20(2) , 186-221, (2013) One part of chemical space that is endowed with interesting biological properties is the area of the chalcones. With this review, we provide a comprehensive overview of the numerous in vivo animal studies on the antineoplastic potential of both natural and sy... |
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Absorption and elimination of (14C) hesperidin methylchalcone in the rat.
Eur. J. Drug Metab. Pharmacokinet. 6(3) , 171-7, (1981) Hesperidin methylchalcone resorption and excretion were studied in rats, using 14C-labelling. The level of radioactivity in the blood showed a peak 1-2 hours after oral administration of the labelled compound, at a dose of 10 mg/kg body weight. The blood kine... |
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Inhibitory effect of the Ruscus extract and of the flavonoid hesperidine methylchalcone on increased microvascular permeability induced by various agents in the hamster cheek pouch.
J. Cardiovasc. Pharmacol. 22(2) , 225-30, (1993) The Ruscus extract and the flavonoid hesperidine methylchalcone (HMC) are used in treatment of venous insufficiency. In the present study, we used the hamster cheek pouch preparation and investigated the effects of these substances on increased microvascular ... |
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Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells.
Int. Immunopharmacol. 8(5) , 670-8, (2008) The fruits of Poncirus trifoliata (L.) are widely used in Oriental medicine to treat allergic inflammation. Recently, several active compounds including hesperidin, hesperidin methyl chalone and phellopterin from P. trifoliata (Rutaceae) were isolated and cha... |
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Effect of Ruscus extract and hesperidin methylchalcone on hypoxia-induced activation of endothelial cells.
Int. Angiol. 18(4) , 306-12, (1999) Ruscus aculeatus extract and the flavonoid hesperidin methylchalcone (HMC) are drugs used in the treatment of chronic venous insufficiency.In the present study, we investigated their effects on the activation of endothelial cells by hypoxia, a condition which... |
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Clinical and capillaroscopic evaluation in the treatment of chronic venous insufficiency with Ruscus aculeatus, hesperidin methylchalcone and ascorbic acid in venous insufficiency treatment of ambulatory patients.
Int. Angiol. 26(4) , 378-84, (2007) Clinical and capillaroscopic evaluation of an association of Ruscus aculeatus, hesperidin methylchalcone (HMC) and ascorbic acid in chronic venous insufficiencyA prospective, multicenter and open clinical study. Chronic venous insufficiency patients were stud... |
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Correlation between improvement in functional signs and plethysmographic parameters during venoactive treatment (Cyclo 3 Fort).
Int. Angiol. 30(3) , 272-7, (2011) The aim of this study was to compare the change in functional signs of venous insufficiency and venous refilling time measured by mercury strain-gauge plethysmography under the effects of the combination of Ruscus aculeatus, hesperidin methylchalcone and asco... |
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Quality of life improvement in Latin American patients suffering from chronic venous disorder using a combination of Ruscus aculeatus and hesperidin methyl-chalcone and ascorbic acid (quality study).
Int. Angiol. 29(6) , 525-32, (2010) The present study assessed the effect of Ruscus aculeatus, hesperidin methyl-chalcone and ascorbic acid (HMC-AA), in the treatment of chronic venous disorders (CVD) in Latin American patients.This study is an observational, single arm, multicentric and prospe... |