前往化源商城

甲基溴化镁

一般危化品
甲基溴化镁结构式
甲基溴化镁结构式
常用名 甲基溴化镁 英文名 METHYLMAGNESIUM BROMIDE
CAS号 75-16-1 分子量 119.24400
密度 1.035 g/mL at 25 °C 沸点 78-80ºC
分子式 CH3BrMg 熔点 0ºC
MSDS 中文版 闪点 77 °F
符号 GHS02 GHS05 GHS07
GHS02, GHS05, GHS07
信号词 Danger

Discovery of dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in neurodegeneration models.

J. Med. Chem. 58(1) , 401-18, (2015)

Dual leucine zipper kinase (DLK, MAP3K12) was recently identified as an essential regulator of neuronal degeneration in multiple contexts. Here we describe the generation of potent and selective DLK inhibitors starting from a high-throughput screening hit. Us...