诃子鞣酸
诃子鞣酸结构式
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常用名 | 诃子鞣酸 | 英文名 | Chebulagic acid |
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| CAS号 | 23094-71-5 | 分子量 | 954.661 | |
| 密度 | 2.1±0.1 g/cm3 | 沸点 | 1610.6±65.0 °C at 760 mmHg | |
| 分子式 | C41H30O27 | 熔点 | >300℃ | |
| MSDS | 中文版 美版 | 闪点 | 480.0±27.8 °C |
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Chemical changes during fermentation of Abhayarishta and its standardization by HPLC-DAD.
Nat. Prod. Commun. 5(4) , 575-9, (2010) Abhayarishta is an Ayurvedic formulation prepared traditionally by the fermentation of the decoction of Terminalia chebula (pericarp), Vitis vinifera (fruits), Embelia ribes (fruits) and Madhuca indica (flowers). In the present communication, chemical changes... |
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[Analysis of tannins in Fructus Chebulae and its confusion varieties by HPCE].
Yao Xue Xue Bao 36(4) , 292-5, (2001) To analyze the hydrolyzable tannins-chebulinic acid (I) and chebulagic acid(II) in Fructus Chebulae and its confusion varieties by using high performance capillary electrophoresis (HPCE) method.Using a capillary (375 microns OD x 50 microns ID; 81.5 cm x 61.5... |
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[Assay of three hydrolyzable tannins in Fructus Chebulae from different habitats by RP-HPLC].
Zhong Yao Cai 23(6) , 328-30, (2000) Three hydrolyzable tannins chebulinic acid (I), chebulagic acid(II) and 1,3, 6-tri-O-galloyl-beta-D-glucose (III) in Fructus Chebulae from different habitats were determined by RP-HPLC method. The contents of I and II were obviously interrelated with the vari... |
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Hydrolysable tannins of tropical almond show antifibrotic effects in TGF-β1-induced hepatic stellate cells.
J. Sci. Food Agric. 91(15) , 2777-84, (2011) Persistent activation of hepatic stellate cells (HSC-T6) has been known to cause liver fibrosis. In this study, our objective was to investigate the effects of chebulagic acid and chebulinic acid, two hydrolysable tannins of tropical almond (Terminalia chebul... |
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Preparative isolation of hydrolysable tannins chebulagic acid and chebulinic acid from Terminalia chebula by high-speed counter-current chromatography.
J. Sep. Sci. 29(11) , 1653-7, (2006) As a chromatographic column, the high-speed counter-current chromatography system was equipped with a preparative HPLC series, enabling the successful isolation of hydrolysable tannins from the fruits of Terminalia chebula, a traditional Chinese medicine. The... |
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Biological activities of phenolic compounds isolated from galls of Terminalia chebula Retz. (Combretaceae).
Nat. Prod. Res. 24(20) , 1915-26, (2010) The aqueous extract of galls from Terminalia chebula Retz. (Combretaceae) was fractionated on Diaion and refractionated on octadecyl silica column. Six phenolic compounds were isolated and identified as gallic acid (1), punicalagin (2), isoterchebulin (3), 1,... |
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In vitro anti-Neisseria gonorrhoeae activity of Terminalia macroptera leaves.
FEMS Microbiol. Lett. 211(2) , 203-6, (2002) We used the agar dilution method to evaluate the antibacterial effect of Terminalia macroptera leaf (Tml) extract against nine reference and clinical Neisseria gonorrhoeae strains, including penicillin- and tetracycline-resistant and -susceptible strains. Tml... |
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Chebulagic acid synergizes the cytotoxicity of doxorubicin in human hepatocellular carcinoma through COX-2 dependant modulation of MDR-1.
Med. Chem. 7(5) , 432-42, (2011) Non-steroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase-2 (COX-2) specific inhibitors are anti-inflammatory agents that have also shown to be useful in anticancer therapy. The effects of chebulagic acid (CA), a benzopyran tannin from Terminalia cheb... |
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Hydrolyzable tannins (chebulagic acid and punicalagin) target viral glycoprotein-glycosaminoglycan interactions to inhibit herpes simplex virus 1 entry and cell-to-cell spread.
J. Virol. 85(9) , 4386-98, (2011) Herpes simplex virus 1 (HSV-1) is a common human pathogen that causes lifelong latent infection of sensory neurons. Non-nucleoside inhibitors that can limit HSV-1 recurrence are particularly useful in treating immunocompromised individuals or cases of emergin... |
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Broad-spectrum antiviral activity of chebulagic acid and punicalagin against viruses that use glycosaminoglycans for entry.
BMC Microbiol. 13 , 187, (2013) We previously identified two hydrolyzable tannins, chebulagic acid (CHLA) and punicalagin (PUG) that blocked herpes simplex virus type 1 (HSV-1) entry and spread. These compounds inhibited viral glycoprotein interactions with cell surface glycosaminoglycans (... |