(-)-双氯甲烷
(-)-双氯甲烷结构式
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常用名 | (-)-双氯甲烷 | 英文名 | (+)-BICUCULLINE METHOCHLORIDE |
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| CAS号 | 38641-83-7 | 分子量 | 417.84000 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C21H20ClNO6 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Effects of halothane on excitatory neurotransmission to medullary expiratory neurons in a decerebrate dog model.
Anesthesiology 93(6) , 1474-81, (2000) The activity of canine expiratory (E) neurons in the caudal ventral respiratory group is primarily dependent on N-methyl-D-aspartic acid (NMDA) receptor-mediated excitatory chemodrive inputs and modulated by an inhibitory mechanism mediated via gamma-aminobut... |
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Influence of genuine kavapyrone enantiomers on the GABA-A binding site.
Planta Med. 64(6) , 504-6, (1998) The influence of kavapyrones from Piper methysticum Forst. on the GABAA receptor was demonstrated using radioreceptor assays. Both the dienolide yangonin and the genuine enolide enantiomers (+)-kavain, (+)-dihydrokavain, (+)-methysticin, and (+)-dihydromethys... |
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Interactions between laudanosine, GABA, and opioid subtype receptors: implication for laudanosine seizure activity.
Brain Res. 646(2) , 235-41, (1994) We examined the interactions of D,L-laudanosine, a potentially epileptogenic metabolite of the neuromuscular relaxant atracurium besylate, with gamma-aminobutyric acid (GABA) and opioid binding sites, all of which have been implicated in seizure activity. Lau... |
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Agrin gene expression in mouse somatosensory cortical neurons during development in vivo and in cell culture.
Neuroscience 79(1) , 191-201, (1997) Agrin is an extracellular matrix protein involved in the formation of the postsynaptic apparatus of the neuromuscular junction. In addition to spinal motor neurons, agrin is expressed by many other neuronal populations throughout the nervous system. Agrin's r... |
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Discriminative stimulus effects of tiagabine and related GABAergic drugs in rats.
Psychopharmacology 197(4) , 591-600, (2008) Tiagabine is an anticonvulsant drug which may also have sleep-enhancing properties. It acts by inhibiting reuptake at the gamma-aminobutyric acid (GABA) transporter (GAT-1).The aim of the study was to determine whether tiagabine acted as a discriminative stim... |
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On the histamine-induced depolarization of the isolated superior cervical ganglion of the rat.
Br. J. Pharmacol. 103(3) , 1752-6, (1991) 1. Using a grease-gap technique, we studied the action of histamine on the d.c. potential recorded between the internal carotid nerve and the main body of the isolated superior cervical ganglion of the rat. 2. A small, slow depolarization was evoked by 10-300... |
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Dynamic differentiation of GABAA-sensitive influences on orientation selectivity of complex cells in the cat striate cortex.
Exp. Brain Res. 104(1) , 81-8, (1995) The influence of GABAA receptors on orientation selectivity of cat complex cells was tested by iontophoresis of the GABAA receptor blockers bicuculline and N-methyl-bicuculline while stimulating with drifting sinusoidal gratings. Reduction of orientation tuni... |
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Habenula as a relay in the descending pathway from nucleus accumbens to periaqueductal grey subserving antinociception.
Int. J. Neurosci. 54(3-4) , 245-51, (1990) This study explored the possibility of a relay at habenula for the descending neural pathway of antinociception. The latency of the escape response elicited by radiant heat on the snout of the rabbit was taken as index of nociception. (1) Microinjection of 20... |
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Adrenergic nerves mediate the venoconstrictor response to PVN stimulation.
Brain Res. 1076(1) , 93-100, (2006) Veins play an important role in the control of venous return, cardiac output and cardiovascular homeostasis. However, the central nervous system sites and effector systems involved in modulating venous function remain to be fully elucidated. The hypothalamic ... |
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Modulation of synaptic transmission in hippocampal CA1 neurons by a novel neurotoxin (beta-pompilidotoxin) derived from wasp venom.
Neurosci. Res. 41(4) , 365-71, (2001) We examined the effects of beta-pompilidotoxin (beta-PMTX), a neurotoxin derived from wasp venom, on synaptic transmission in the mammalian central nervous system (CNS). Using hippocampal slice preparations of rodents, we made both extracellular and intracell... |