胞嘧啶
胞嘧啶结构式
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常用名 | 胞嘧啶 | 英文名 | cytosine |
|---|---|---|---|---|
| CAS号 | 71-30-7 | 分子量 | 111.102 | |
| 密度 | 1.6±0.1 g/cm3 | 沸点 | 445.8ºC at 760 mmHg | |
| 分子式 | C4H5N3O | 熔点 | >300 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 223.4ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Cyclic di-GMP riboswitch-regulated type IV pili contribute to aggregation of Clostridium difficile.
J. Bacteriol. 197(5) , 819-32, (2015) Clostridium difficile is an anaerobic Gram-positive bacterium that causes intestinal infections with symptoms ranging from mild diarrhea to fulminant colitis. Cyclic diguanosine monophosphate (c-di-GMP) is a bacterial second messenger that typically regulates... |
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Dynamic switching of active promoter and enhancer domains regulates Tet1 and Tet2 expression during cell state transitions between pluripotency and differentiation.
Mol. Cell. Biol. 35(6) , 1026-42, (2015) The Tet 5-methylcytosine dioxygenases catalyze DNA demethylation by producing 5-hydroxymethylcytosine and further oxidized products. Tet1 and Tet2 are highly expressed in mouse pluripotent cells and downregulated to different extents in somatic cells, but the... |
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ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion.
Cell Death Differ. 22 , 1970-84, (2015) Trophoblasts, placental cells of epithelial lineage, undergo extensive differentiation to form the cellular components of the placenta. Trophoblast progenitor cell differentiation into the multinucleated syncytiotrophoblast is a key developmental process requ... |
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Post-conversion targeted capture of modified cytosines in mammalian and plant genomes.
Nucleic Acids Res. 43 , e81, (2015) We present a capture-based approach for bisulfite-converted DNA that allows interrogation of pre-defined genomic locations, allowing quantitative and qualitative assessments of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) at CG dinucleotides and ... |
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Selective self-assembly of adenine-silver nanoparticles forms rings resembling the size of cells.
Sci. Rep. 5 , 17805, (2015) Self-assembly has played critical roles in the construction of functional nanomaterials. However, the structure of the macroscale multicomponent materials built by the self-assembly of nanoscale building blocks is hard to predict due to multiple intermolecula... |
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Preparation and chromatographic evaluation of a newly designed steviol glycoside modified-silica stationary phase in hydrophilic interaction liquid chromatography and reversed phase liquid chromatography.
J. Chromatogr. A. 1388 , 110-8, (2015) A diterpene glycoside compound, rebaudioside A (commonly abbreviated as RA), was immobilized onto porous silica surface through "thiol-ene" click chemistry strategy. The successful immobilization of the RA on the silica support was confirmed by FT-IR and elem... |
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Simultaneous quantification of purine and pyrimidine bases, nucleosides and their degradation products in bovine blood plasma by high performance liquid chromatography tandem mass spectrometry.
J. Chromatogr. A. 1356 , 197-210, (2014) Improved nitrogen utilization in cattle is important in order to secure a sustainable cattle production. As purines and pyrimidines (PP) constitute an appreciable part of rumen nitrogen, an improved understanding of the absorption and intermediary metabolism ... |
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Separation of therapeutic peptides with cyclofructan and glycopeptide based columns in hydrophilic interaction liquid chromatography.
J. Chromatogr. A. 1390 , 50-61, (2015) Three cyclofructan-based, two glycopeptide-based, and one zwitterionic column used in the HILIC mode were assessed within a graphical framework based on different functional characteristics contributing to selectivity. The characteristics of these six HILIC c... |
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Origin of life. From hell on Earth, life's building blocks.
Science 346(6215) , 1279, (2014)
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Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation.
Blood 123(17) , e79-89, (2014) In development, epigenetic mechanisms such as DNA methylation have been suggested to provide a cellular memory to maintain multipotency but also stabilize cell fate decisions and direct lineage restriction. In this study, we set out to characterize changes in... |