环戊丙酸雌二醇
环戊丙酸雌二醇结构式
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常用名 | 环戊丙酸雌二醇 | 英文名 | Estradiol Cypionate |
|---|---|---|---|---|
| CAS号 | 313-06-4 | 分子量 | 396.562 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 532.8±50.0 °C at 760 mmHg | |
| 分子式 | C26H36O3 | 熔点 | ≥300 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 207.7±22.9 °C | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger |
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Premature estrogen exposure alters endometrial gene expression to disrupt pregnancy in the pig.
Endocrinology 148(10) , 4761-73, (2007) Establishment and maintenance of pregnancy in the pig involve intricate communication between the developing conceptuses and maternal endometrium. Conceptus synthesis and release of estrogen during trophoblastic elongation are essential factors involved with ... |
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Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats.
J. Neuroimmunol. , (2008) Estrogen has been shown to attenuate the inflammatory response following injury or lipopolysaccharide treatment in several organ systems. Estrogen's actions are transduced through two estrogen receptor sub-types, estrogen receptor (ER) -alpha and estrogen rec... |
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Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations inBos indicuscows submitted to a timed artificial insemination protocol
Theriogenology 78(3) , 510-6, (2012) The effects of estradiol benzoate (EB) and estradiol cypionate (EC) on induction of ovulation after a synchronized LH surge and on fertility of Bos indicus females submitted to timed AI (TAI) were evaluated. In Experiment 1, ovariectomized Nelore heifers were... |
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Impact of estrogen replacement on letrozole-induced embryopathic effects.
Hum. Reprod. 24(11) , 2688-92, (2009) The aromatase inhibitor, letrozole, exerts embryo toxic effects in rats, causing increased embryo lethality and anomalies of the axial skeleton at pharmacologically relevant doses. Letrozole acts by inhibiting estrogen biosynthesis. It may thus be feasible th... |
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The effect of flushing and stimulus of estrogenized does on reproductive performance of anovulatory-range goats.
Trop. Anim. Health Prod. 43(8) , 1595-600, (2011) This study was conducted to determine whether flushing or the stimulus of estrogenized goats is necessary to achieve a high reproductive response in anestrous goats on rangeland. Does were feed-supplemented on rangeland (flushed, n = 20). Other group was expo... |
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Development of estrous synchronization protocols using melengestrol acetate in Bos indicus cattle.
J. Anim. Sci. 87(6) , 1981-90, (2009) Five experiments were conducted on commercial farms in Brazil designed to develop the basis for an estrus synchronization protocol using melengestrol acetate (MGA) in Bos indicus cattle. These studies resulted in the development of the following protocol: 0.5... |
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Short communication: Effect of estrogen supplemented at dry-off on temporal changes in concentrations of lactose in blood plasma of Holstein cows.
J. Dairy Sci. 92(8) , 3815-8, (2009) The objective was to determine the effect of supplemental estrogen (estradiol cypionate, ECP) at dry-off on temporal changes in concentrations of lactose in blood plasma of Holstein cows as an indicator of rate of mammary involution. Thirty-two Holstein cows ... |
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Endometrial gene expression of acute phase extracellular matrix components following estrogen disruption of pregnancy in pigs.
Anim. Reprod. Sci. 122(3-4) , 215-21, (2010) In pigs, administration of estrogen to gilts on Days 9 and 10 of pregnancy causes conceptus fragmentation and death between Days 15 and 18 of gestation. Conceptus degeneration is associated with breakdown of the microvilli surface glycocalyx on the lumenal ep... |
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Comparative pharmacokinetics and pharmacodynamics after subcutaneous and intramuscular administration of medroxyprogesterone acetate (25 mg) and estradiol cypionate (5 mg)
Contraception 84(6) , 565-70, (2011) Background The efficacy of contraceptives is affected by its route and ease of administration. Herein, both pharmacokinetics and pharmacodynamics of the once-a-month combined injectable contraceptive medroxyprogesterone acetate (MPA) plus estradiol cypionate ... |
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Endometrial caspase 1 and interleukin-18 expression during the estrous cycle and peri-implantation period of porcine pregnancy and response to early exogenous estrogen administration.
Reprod. Biol. Endocrinol. 8 , 33, (2010) The role for endometrial secretion of cytokines during the establishment of pregnancy in a number of mammals is well established. The current study determined endometrial expression of caspase 1 (CASP1) and interleukin-18 (IL18) during the estrous cycle and e... |