苄达明氮氧化物 马来酸氢盐
苄达明氮氧化物 马来酸氢盐结构式
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常用名 | 苄达明氮氧化物 马来酸氢盐 | 英文名 | BENZYDAMINE N-OXIDE HYDROGEN MALEATE |
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| CAS号 | 72962-60-8 | 分子量 | 441.47700 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C23H27N3O6 | 熔点 | 94-95ºC | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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HPLC determination of benzydamine and its metabolite N-oxide in plasma following oral administration or topical application in man, using fluorimetric detection.
Pharmacol. Res. Commun. 18(4) , 385-403, (1986) A method for the extraction and quantification of benzydamine and its metabolite N-oxide by liquid chromatography with fluorescence detection in plasma samples is described. This method has adequate sensitivity, specificity and is reproducible. The use of the... |
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Determination of benzydamine and its N-oxide in biological fluids by high-performance liquid chromatography.
J. Chromatogr. A. 529(1) , 113-23, (1990) A simple, sensitive and selective method for the determination of benzydamine in human plasma and urine, and for benzydamine N-oxide in urine, has been developed using high-performance liquid chromatography in the reversed-phase mode. The limit of reliable de... |
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Flavin-containing monooxygenase mediated metabolism of benzydamine in perfused brain and liver.
Biochim. Biophys. Acta 1425(1) , 41-6, (1998) Benzydamine (BZY) N-oxidation mediated by flavin-containing monooxygenase (FMO) was evaluated in perfused brain and liver. Following 20 min of perfusion with modified Ringer solution, the infusion of BZY into brain or liver led to production of BZY N-oxide. B... |
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Biotransformation of benzydamine by microsomes and precision-cut slices prepared from cattle liver.
Xenobiotica 32(1) , 73-86, (2002) 1. Benzydamine (BZ), a non-steroidal anti-inflammatory drug used in human and veterinary medicine, is not licensed for use in food-producing species. Biotransformation of BZ in cattle has not been reported previously and is investigated here using liver micro... |
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Can caffeine metabolism be used as an in-vivo probe for human flavin-containing monooxygenase activity?
Pharmacogenetics 10(3) , 275-7, (2000)
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