N,N-二甲基-4-亚硝基苯胺
一般危化品
N,N-二甲基-4-亚硝基苯胺结构式
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常用名 | N,N-二甲基-4-亚硝基苯胺 | 英文名 | N,N-Dimethyl-4-nitrosoaniline |
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| CAS号 | 138-89-6 | 分子量 | 150.178 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 258.7±23.0 °C at 760 mmHg | |
| 分子式 | C8H10N2O | 熔点 | 85-87 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 110.3±22.6 °C | |
| 符号 |
GHS02, GHS06 |
信号词 | Danger |
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Role of type I & type II radicals in DNA damage and activation of Caspase 3 via mitochondrial pathway induced by photosensitized benzophenone
Toxicol. Lett. 235(2) , 84-95, (2015) [Display omitted] |
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Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools.
Regul Toxicol Pharmacol 72 , 578-85, (2015) Previously, a non-animal screening approach was proposed for evaluating photosafety of cosmetic ingredients by means of in vitro photochemical and photobiochemical assays; however, complex cosmetic ingredients, such as plant extracts and polymers, could not b... |
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Phototoxic Risk Assessments on Benzophenone Derivatives: Photobiochemical Assessments and Dermal Cassette-Dosing Pharmacokinetic Study.
J. Pharmacol. Exp. Ther. 354 , 195-202, (2015) This study aimed to qualify photosafety screening on the basis of photochemical and pharmacokinetic (PK) data on dermally applied chemicals. Six benzophenone derivatives (BZPs) were selected as model compounds, and in vitro photochemical/phototoxic characteri... |
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Inactivation of bacteria via photosensitization of vitamin K3 by UV-A light.
FEMS Microbiol. Lett. 358(1) , 98-105, (2014) This study investigated inactivation of bacteria with ultraviolet light A irradiation in combination with vitamin K3 as a photosensitizer. Six bacteria including Bacillus cereus, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis, Klebs... |
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Dietary exposure and urinary excretion of total N-nitroso compounds, nitrosamino acids and volatile nitrosamine in inhabitants of high- and low-risk areas for esophageal cancer in southern China.
Int. J. Cancer 102(3) , 207-11, (2002) We assessed the exposure of total N-nitroso compounds (TNOCs) in the inhabitants of high- and low-risk areas for esophageal cancer in southern China. Samples of 24 hr diet and 12 hr overnight urine were collected from 120 male adults in each of the 2 areas, a... |
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Photoprotective efficiency of PLGA-curcumin nanoparticles versus curcumin through the involvement of ERK/AKT pathway under ambient UV-R exposure in HaCaT cell line.
Biomaterials 84 , 25-41, (2016) Curcumin (Cur) has been demonstrated to have wide pharmacological window including anti-oxidant and anti-inflammatory properties. However, phototoxicity under sunlight exposure and poor biological availability limits its applicability. We have synthesized bio... |
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NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D(2) and serotonin 5-HT(2)receptors-implications for models of schizophrenia.
Mol. Psychiatry 7(8) , 837-44, (2002) Ketamine and PCP are commonly used as selective NMDA receptor antagonists to model the putative hypoglutamate state of schizophrenia and to test new antipsychotics. Recent findings question the NMDA receptor selectivity of these agents. To examine this furthe... |
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A N-Nitrosodimethylamine (NDMA) precursor analysis for chlorination of water and wastewater.
Water Res. 37(15) , 3733-41, (2003) N-nitrosodimethylamine (NDMA) is a potent carcinogen formed during chloramination of water and wastewater treatment plant effluents. A procedure is described for quantifying the concentration of the organic precursors of NDMA that could be formed during chlor... |
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Influence of the order of reagent addition on NDMA formation during chloramination.
Environ. Sci. Technol. 39(10) , 3811-8, (2005) The formation of the potent carcinogen, N-nitrosodimethylamine (NDMA), during chlorine disinfection has caused significant concern among drinking water and wastewater recycling utilities practicing intentional or unintentional chloramination. Previous researc... |
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Prostaglandin EP1 receptor contributes to excitotoxicity and focal ischemic brain damage.
Toxicol. Sci. 89(1) , 265-70, (2006) The clinical side effects associated with the inhibition of cyclooxygenase enzymes under pathologic conditions have recently raised concerns. A better understanding of neuroinflammatory mechanisms and neuronal survival requires knowledge of cyclooxygenase dow... |