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5,6-亚甲二氧基-2-氨基茚满

一般危化品
5,6-亚甲二氧基-2-氨基茚满结构式
5,6-亚甲二氧基-2-氨基茚满结构式
常用名 5,6-亚甲二氧基-2-氨基茚满 英文名 MDAI
CAS号 132741-81-2 分子量 177.200
密度 1.3±0.1 g/cm3 沸点 312.4±31.0 °C at 760 mmHg
分子式 C10H11NO2 熔点 N/A
MSDS N/A 闪点 155.9±32.1 °C
符号 GHS02 GHS07
GHS02, GHS07
信号词 Danger

Central cyanosis on a psychiatric unit treated at the Salford Royal Hospital.

Thorax 69(12) , 1157-8, (2014)

We describe a case of acquired methaemoglobinaemia due to frequent use of the 'legal high' known as 'Pink Panthers'. This contains 5,6-Methylenedioxy-2-aminoindane and 2-Aminoindane, both amphetamine analogues with the potential to cause methaemoglobinaemia. ...

Studies on the mechanism of p-chloroamphetamine neurotoxicity.

Biochem. Pharmacol. 52 , 1271-1277, (1996)

Studies were conducted to investigate the sensitivity of p-chloroamphetamine (PCA)-induced neurochemical changes to various pharmacological manipulations known to block the neurochemical effects of 3,4-methylenedioxymethamphetamine (MDMA). The monoamine oxida...

GHB and synthetic cathinones: clinical effects and potential consequences.

Drug Test. Anal. 3(9) , 552-9, (2011)

Designer drugs belong to a group of legally or illegally produced substances that are structurally and pharmacologically very similar to illicit drugs. In the past, designer drugs were often used during all-night dance parties, but they are now consumed in mu...

An analysis of legal highs: do they contain what it says on the tin?

Drug Test. Anal. 3(9) , 576-81, (2011)

In recent years the availability of so-called legal highs over the Internet has hugely increased. Numerous online legal-high retailers market a broad variety of products which are advertised as research chemicals, bath salts, or plant food although clearly in...

(+)-N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine as a discriminative stimulus in studies of 3,4-methylenedioxy-methamphetamine-like behavioral activity.

J. Pharmacol. Exp. Ther. 255(3) , 1098-106, (1990)

The stimulus properties of 3,4-methylenedioxymethamphetamine (MDMA)-like compounds were studied in rats trained to discriminate saline from (+)-N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine [(+)-MBDB] hydrochloride (7.18 mumol/kg; 1.75 mg/kg), the alpha-ethy...

5,6-Methylenedioxy-2-aminoindane: from laboratory curiosity to 'legal high'.

Hum. Psychopharmacol. Clin. Exp. 27(2) , 106-12, (2012)

The fully synthetic 'legal high' 5,6-methylenedioxy-2-aminoindane (MDAI) is an analogue of 3,4-methylenedioxymethamphetamine. Although developed in the 1990s, it was not widely abused until 2010. However, mephedrone was banned in the UK in April 2010, and alm...

Reference materials for new psychoactive substances.

Drug Test. Anal. 3(7-8) , 505-14, (2011)

Historically, the appearance of new psychoactive materials (and hence the requirement for new reference standards) has been relatively slow. This position has now changed, with 101 new psychoactive substances reported to EMCDDA-Europol since 2006. The newly r...

Serotonin neurotoxicity in rats after combined treatment with a dopaminergic agent followed by a nonneurotoxic 3,4-methylenedioxymethamphetamine (MDMA) analogue.

Pharmacol. Biochem. Behav. 40(4) , 915-22, (1991)

There is increasing evidence linking dopamine (DA) to the long-term serotonergic (5-HT) neurotoxic effects of certain substituted amphetamines such as 3,4-methylenedioxymethamphetamine (MDMA). The present study was undertaken to examine the importance of DA m...