Hemokinin 1, human
Hemokinin 1, human结构式
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常用名 | Hemokinin 1, human | 英文名 | Hemokinin 1 (human) trifluoroacetate salt |
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| CAS号 | 491851-53-7 | 分子量 | 1184.39000 | |
| 密度 | 1.282 g/cm3 | 沸点 | 1669.168ºC at 760 mmHg | |
| 分子式 | C54H84N14O14S | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 963.278ºC |
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Centrally administered hemokinin-1 (HK-1), a neurokinin NK1 receptor agonist, produces substance P-like behavioral effects in mice and gerbils.
Neuropharmacology 45(2) , 242-50, (2003) Hemokinin-1 (HK-1) is a recently described mouse tachykinin peptide whose biological functions are not fully understood. To date, a unique receptor for HK-1 has not been identified. Recent studies suggest HK-1 may have a role in immunological functions, but t... |
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T-cell developmental blockage by tachykinin antagonists and the role of hemokinin 1 in T lymphopoiesis.
Blood 102(6) , 2165-72, (2003) Hemokinin 1 (HK-1) is a new member of the tachykinin peptide family that is expressed in hematopoietic cells. Recent reports studying mouse, rat, and human orthologs of HK-1 demonstrate a broader distribution than originally reported. Our previous studies dem... |
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Characterization of the endokinins: human tachykinins with cardiovascular activity.
Proc. Natl. Acad. Sci. U. S. A. 100 , 6245-6250, (2003) We report four human tachykinins, endokinins A, B, C, and D (EKA-D), encoded from a single tachykinin precursor 4 gene that generates four mRNAs (alpha, beta, gamma, and delta). Tachykinin 4 gene expression was detected primarily in adrenal gland and in the p... |
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Newly discovered tachykinins raise new questions about their peripheral roles and the tachykinin nomenclature.
Trends Pharmacol. Sci. 25 , 1-3, (2004) The tachykinin family has recently been extended by the discovery of a third tachykinin gene encoding previously unknown mammalian tachykinins (hemokinin 1, endokinin A and endokinin B) that have a widespread peripheral distribution and a tachykinin NK(1) rec... |
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Expression and function of human hemokinin-1 in human and guinea pig airways.
Respir. Res. 11 , 139, (2010) Human hemokinin-1 (hHK-1) and endokinins are peptides of the tachykinin family encoded by the TAC4 gene. TAC4 and hHK-1 expression as well as effects of hHK-1 in the lung and airways remain however unknown and were explored in this study.RT-PCR analysis was p... |