Hemokinin 1 (human) trifluoroacetate salt

Modify Date: 2024-01-02 21:18:50

Hemokinin 1 (human) trifluoroacetate salt structure	Common Name	Hemokinin 1 (human) trifluoroacetate salt
	CAS Number	491851-53-7	Molecular Weight	1184.39000
	Density	1.282 g/cm3	Boiling Point	1669.168ºC at 760 mmHg
	Molecular Formula	C₅₄H₈₄N₁₄O₁₄S	Melting Point	N/A
	MSDS	USA	Flash Point	963.278ºC

Use of Hemokinin 1 (human) trifluoroacetate salt

Hemokinin 1, human is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human can produces an opioid-independent analgesia[1][2].

Name	Hemokinin 1 (human)
Synonym	More Synonyms

Description	Hemokinin 1, human is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human can produces an opioid-independent analgesia[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
References	[1]. Cai-Yun Fu, et al. Hemokinin-1(4-11)-induced analgesia selectively up-regulates δ-opioid receptor expression in mice. PLoS One [2]. Francesca Bellucci, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol. 2002 Jan;135(1):266-74.

Description

Related Catalog

Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor

References

[1]. Cai-Yun Fu, et al. Hemokinin-1(4-11)-induced analgesia selectively up-regulates δ-opioid receptor expression in mice. PLoS One

[2]. Francesca Bellucci, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol. 2002 Jan;135(1):266-74.

Density	1.282 g/cm3
Boiling Point	1669.168ºC at 760 mmHg
Molecular Formula	C₅₄H₈₄N₁₄O₁₄S
Molecular Weight	1184.39000
Flash Point	963.278ºC
Exact Mass	1183.59000
PSA	480.99000
LogP	1.08700

MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

Centrally administered hemokinin-1 (HK-1), a neurokinin NK1 receptor agonist, produces substance P-like behavioral effects in mice and gerbils.

Neuropharmacology 45(2) , 242-50, (2003)

Hemokinin-1 (HK-1) is a recently described mouse tachykinin peptide whose biological functions are not fully understood. To date, a unique receptor for HK-1 has not been identified. Recent studies sug...

T-cell developmental blockage by tachykinin antagonists and the role of hemokinin 1 in T lymphopoiesis.

Blood 102(6) , 2165-72, (2003)

Hemokinin 1 (HK-1) is a new member of the tachykinin peptide family that is expressed in hematopoietic cells. Recent reports studying mouse, rat, and human orthologs of HK-1 demonstrate a broader dist...

Characterization of the endokinins: human tachykinins with cardiovascular activity.

Proc. Natl. Acad. Sci. U. S. A. 100 , 6245-6250, (2003)

We report four human tachykinins, endokinins A, B, C, and D (EKA-D), encoded from a single tachykinin precursor 4 gene that generates four mRNAs (alpha, beta, gamma, and delta). Tachykinin 4 gene expr...

h-thr-gly-lys-ala-ser-gln-phe-phe-gly-leu-met-nh2

thr-gly-lys-ala-ser-gln-phe-phe-gly-leu-met-nh2

hhk-1