氰乙酰胺
氰乙酰胺结构式
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常用名 | 氰乙酰胺 | 英文名 | 2-Cyanoacetamide |
|---|---|---|---|---|
| CAS号 | 107-91-5 | 分子量 | 84.077 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 246.1±42.0 °C at 760 mmHg | |
| 分子式 | C3H4N2O | 熔点 | 119-121 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 102.6±27.9 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Diversity-oriented, one-pot, multi-component synthesis of substituted uracil derivatives.
Mol. Divers. 15(1) , 263-7, (2011) With the emergence of high throughput screening of bioactive molecules, there is constant need for the development of new strategies for diversity-oriented synthesis. We describe here a novel one-pot multicomponent reaction for the synthesis of uracil derivat... |
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Controlled synthesis of Fe3O4/ZIF-8 nanoparticles for magnetically separable nanocatalysts.
Chemistry 21(18) , 6879-87, (2015) Fe3O4/ZIF-8 nanoparticles were synthesized through a room-temperature reaction between 2-methylimidazolate and zinc nitrate in the presence of Fe3O4 nanocrystals. The particle size, surface charge, and magnetic loading can be conveniently controlled by the do... |
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Acylation of heteroaromatic amines: facile and efficient synthesis of a new class of 1,2,3-triazolo[4,5-b]pyridine and pyrazolo[4,3-b]pyridine derivatives.
Molecules 16(5) , 3723-39, (2011) 1,2,3-Triazolo[4,5-b]pyridines and pyrazolo[4,3-b]pyridines can be readily prepared via cyanoacetylation reactions of 5-amino-1,2,3-triazoles 1a,b and 4-amino- pyrazole 2 followed by subsequent cyclization of the formed cyanoacetamides. Reactions of amines 1a... |
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A novel α-isocyanoacetamide-based three-component reaction for the synthesis of dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates.
Org. Biomol. Chem. 9(5) , 1627-31, (2011) α-Isocyanoacetamides, acyl chlorides and dialkylacetylenedicarboxylates undergo a smooth multicomponent reaction to produce dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates in good yield. The scope and mechanism of this new multicomponent transformation are dis... |
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Kinetic and mechanistic analyses of new classes of inhibitors of two-component signal transduction systems using a coupled assay containing HpkA-DrrA from Thermotoga maritima.
Microbiology 150(Pt 4) , 885-96, (2004) Two-component signal transduction systems (TCSs) play fundamental roles in bacterial survival and pathogenesis and have been proposed as targets for the development of novel classes of antibiotics. A new coupled assay was developed and applied to analyse the ... |
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An ultraviolet-spectrophotometric method with 2-cyanoacetamide for the determination of the enzymatic degradation of reducing polysaccharides.
Anal. Biochem. 203 , 335-339, (1992) A rapid, facile, and sensitive uv-spectrophotometric assay has been developed for the determination of the enzymatic degradation of polysaccharides that generates reducing sugars. The assay was carried out with 2-cyanoacetamide in a single test tube. The solu... |
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Microdetermination of hyaluronan in human plasma by high-performance liquid chromatography with a graphitized carbon column and postcolumn fluorometric detection.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(13-14) , 950-4, (2011) A chemical method for the determination of hyaluronan (hyaluronic acid, HA) has been developed and applied to the human blood plasma. Human blood plasma HA was converted to the ΔDi-HA by digestion with hyaluronidase SD and determined by a sensitive and select... |
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Spectrofluorimetric determination of prenalterol hydrochloride in pharmaceutical preparations and biological fluids.
J. Pharm. Biomed. Anal. 18(6) , 993-7, (1999) A simple and highly sensitive fluorimetric method was developed for the routine determination of prenalterol hydrochloride in bulk, in dosage forms and in biological fluids. The method is based on the fluorescence induced by reaction of the nitroso-derivative... |
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Spectrofluorimetric method for determination and validation of cefixime in pharmaceutical preparations through derivatization with 2-cyanoacetamide.
J. Fluoresc. 21(2) , 579-85, (2011) A simple, sensitive and accurate method has been developed for spectrofluorimetric determination of cefixime in pure form and pharmaceutical preparations. The method is based on the reaction of cefixime with 2-cyanoacetamide in the presence of 21% ammonia at ... |
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Determination of ubiquinone in blood by high-performance liquid chromatography with post-column fluorescence derivatization using 2-cyanoacetamide.
J. Fluoresc. 21 , 2093-2100, (2011) It was shown that ubiquinone (CoQ(10)) and ubiquinol (CoQ(10)H(2)) produce fluorescence products under alkaline conditions when reacted with 2-cyanoacetamide. The reaction mixture from CoQ(10) gave fluorescence with excitation and emission maximum wavelengths... |