1-甲基组胺二盐酸盐
1-甲基组胺二盐酸盐结构式
|
常用名 | 1-甲基组胺二盐酸盐 | 英文名 | 1-Methylhistamine dihydrochloride |
|---|---|---|---|---|
| CAS号 | 6481-48-7 | 分子量 | 161.63300 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C6H13Cl2N3 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Hair analysis of histamine and several metabolites in C3H/HeNCrj mice by ultra performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry (UPLC-ESI-TOF-MS): influence of hair cycle and age.
Clin. Chim. Acta 378(1-2) , 122-7, (2007) According to a previous study, the concentration of HA in the hair of SD rats was similar in each rat and the variation in HA concentration was not so great. However, the concentration in human hair was fairly different in each person. As possible reasons for... |
|
|
The interaction of parafluorohexahydrosiladiphenidol at muscarinic receptors in vitro.
Br. J. Pharmacol. 99 , 637, (1990) 1. The antagonistic actions of parafluorohexahydrosiladiphenidol (pFHHSiD) at muscarinic receptors has been studied in cardiac muscle, smooth muscle and cell culture preparations. In this paper, the classification scheme of Doods et al. (1987) is employed. Th... |
|
|
High-performance liquid chromatographic determination of histamine in biological samples: the cerebrospinal fluid challenge--a review.
Anal. Chim. Acta 774 , 1-10, (2013) Histamine, a neurotransmitter crucially involved in a number of basic physiological functions, undergoes changes in neuropsychiatric disorders. Detection of histamine in biological samples such as cerebrospinal fluid (CSF) is thus of clinical importance. The ... |
|
|
Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.
J. Med. Chem. 47(12) , 3264-74, (2004) 4-(3-Aryloxypropyl)-1H-imidazoles, which possess a meta-positioned substituent in the aryl ring, have been synthesized and tested for activity at histamine H(3) receptors. The compounds having a CN, Me, or Br substituent were found to be antagonists, whereas ... |
|
|
Hypothalamic neuronal histamine in genetically obese animals: its implication of leptin action in the brain.
Exp. Biol. Med. (Maywood.) 228(10) , 1132-7, (2003) Leptin regulates feeding behavior and energy metabolism by affecting hypothalamic neuromodulators. The present study was designed to examine hypothalamic neuronal histamine, a recently identified mediator of leptin signaling in the brain, in genetic obese ani... |
|
|
Effect of interleukin 1beta on the HPA axis in H1-receptor knockout mice.
Neuroimmunomodulation 10(6) , 344-50, (2002) Circulating cytokines such as interleukin-1 (IL-1), and tumor necrosis factor-alpha as well as lipopolysaccharide (LPS) are potent ACTH secretagogues, acting via stimulation of corticotropin-releasing hormone (CRH) and vasopressinergic neurons in the paravent... |
|
|
Simultaneous fluorometric measurement of histamine and tele-methylhistamine levels in rodent brain by high-performance liquid chromatography.
Anal. Biochem. 334(1) , 89-96, (2004) An improved high-performance liquid chromatography (HPLC) method was developed for simultaneous analysis of histamine (HA) and tele-methylhistamine (tele-MHA) levels in mouse and rat brain. The method consists of a solid-phase extraction (SPE) and subsequent ... |
|
|
Inhibition of basophil activation by histamine: a sensitive and reproducible model for the study of the biological activity of high dilutions.
Homeopathy 98(4) , 186-97, (2009) At the beginning of this series of experiments we were looking for a model based on the use of purified commercially available compounds based on a fully described and accepted pharmacological model to study of the biological effect of high dilutions. Negativ... |
|
|
Acute central administration of immepip, a histamine H3 receptor agonist, suppresses hypothalamic histamine release and elicits feeding behavior in rats.
Brain Res. Bull. 79(1) , 37-40, (2009) Histamine suppresses feeding behavior via histamine H1 receptors in the hypothalamus. This study was performed to examine whether the acute reduction of histamine release in the hypothalamus caused by immepip, a histamine H3 agonist, modulates the feeding beh... |
|
|
Alcoholics show altered histaminergic neurotransmission in several cortical areas--preliminary report.
Inflamm. Res. 52 Suppl 1 , S37-8, (2003)
|