(R)-(+)-2-溴-3-甲基丁酸
(R)-(+)-2-溴-3-甲基丁酸结构式
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常用名 | (R)-(+)-2-溴-3-甲基丁酸 | 英文名 | UNII:M69LGV465C |
|---|---|---|---|---|
| CAS号 | 76792-22-8 | 分子量 | 181.028 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 230.0±0.0 °C at 760 mmHg | |
| 分子式 | C5H9BrO2 | 熔点 | 35-40ºC(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 107.2±0.0 °C | |
| 符号 |
GHS05, GHS07 |
信号词 | Danger |
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Glutathione conjugation of the alpha-bromoisovaleric acid enantiomers in the rat in vivo and its stereoselectivity. Pharmacokinetics of biliary and urinary excretion of the glutathione conjugate and the mercapturate.
Biochem. Pharmacol. 38(22) , 3957-62, (1989) The glutathione (GSH) conjugation of (R)-and (S)-alpha-bromoisovaleric acid (BI) in the rat in vivo, and its stereoselectivity, have been characterized. After administration of racemic [1-14C]BI two radioactive metabolites were found in bile: only one of the ... |
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Stereoselectivity of rat liver glutathione transferase isoenzymes for alpha-bromoisovaleric acid and alpha-bromoisovalerylurea enantiomers.
Biochem. J. 252(1) , 137-42, (1988) The stereoselectivity of purified rat GSH transferases towards alpha-bromoisovaleric acid (BI) and its amide derivative alpha-bromoisovalerylurea (BIU) was investigated. GSH transferase 2-2 was the only enzyme to catalyse the conjugation of BI and was selecti... |
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Stereoselective conjugation of 2-bromocarboxylic acids and their urea derivatives by rat liver glutathione transferase 12-12 and some other isoforms.
Biochem. Pharmacol. 44(7) , 1249-53, (1992) Glutathione (GSH) conjugation of the separate enantiomers of five 2-bromocarboxylic acids and some of their urea derivatives by rat liver GSH transferases (GSTs) was studied. The liver cytosolic fraction conjugated all compounds, except for (R)-2-bromoisovale... |