1,1'-二乙基-2,2'-碘化氰
1,1'-二乙基-2,2'-碘化氰结构式
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常用名 | 1,1'-二乙基-2,2'-碘化氰 | 英文名 | 1,1'-Diethyl-2,2'-cyanine iodide |
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| CAS号 | 977-96-8 | 分子量 | 454.34700 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C23H23IN2 | 熔点 | 273ºC | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS06 |
信号词 | Danger |
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Decynium-22 enhances SSRI-induced antidepressant-like effects in mice: uncovering novel targets to treat depression.
J. Neurosci. 33(25) , 10534-43, (2013) Mood disorders cause much suffering and lost productivity worldwide, compounded by the fact that many patients are not effectively treated by currently available medications. The most commonly prescribed antidepressant drugs are the selective serotonin (5-HT)... |
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Involvement of the organic cation transporters in histamine uptake into human vascular endothelial cells.
Inflamm. Res. 58 Suppl 1 , 61-2, (2009)
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Local inhibition of organic cation transporters increases extracellular serotonin in the medial hypothalamus.
Brain Res. 1063(1) , 69-76, (2005) In the rat dorsomedial hypothalamus (DMH), serotonin (5-HT) concentrations are altered rapidly in response to acute stressors. The mechanism for rapid changes in 5-HT concentrations in the DMH is not clear. We hypothesize that the mechanism involves corticost... |
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Modulation of MPP+ uptake by tea and some of its components in Caco-2 cells.
Naunyn Schmiedebergs Arch. Pharmacol. 372(2) , 147-52, (2005) The entry of most xeno/endobiotics into the organism is limited by their intestinal absorption. The interference of certain foods with the therapeutic efficacy of drugs or with chemical toxicity is becoming evident and growing attention is being given to thes... |
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Studies on the interaction of achiral cationic pseudoisocyanine with chiral metal complexes.
Phys. Chem. Chem. Phys. 13(37) , 16741-7, (2011) The effect of chiral metal complexes ([Co(en)(3)]I(3)·H(2)O, cis-[CoBr(NH(3))(en)(2)]Br(2), K[Co(edta)]·2H(2)O and [Ru(phen)(3)](PF(6))(2)) on the polymer-bound J-aggregates in aqueous mixtures of pesudoisocyanine (PIC) iodine and poly(acrylic acid, sodium)(P... |
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A purine-selective nucleobase/nucleoside transporter in PK15NTD cells.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 294(6) , R1988-95, (2008) Nucleoside and nucleobase transporters are important for salvage of purines and pyrimidines and for transport of their analog drugs into cells. However, the pathways for nucleobase translocation in mammalian cells are not well characterized. We identified an ... |
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Mega three-photon absorption cross-section enhancement in pseudoisocyanine J-aggregates.
J. Chem. Phys. 123(23) , 231104, (2005) Herein we report an extraordinary three-photon absorption cross-section (sigma'3) enhancement in J-aggregates supramolecular systems. The much higher value of sigma'3 in PIC J-aggregate (2.5 x 10(-71) cm6 s2 ph(-2)) compared to typical values obtained in orga... |
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Effect of organic solvents on J aggregation of pseudoisocyanine dye at mica/water interfaces: morphological transition from three-dimension to two-dimension.
J. Colloid. Interface Sci. 318(1) , 116-23, (2008) Morphological and spectroscopic properties of pseudoisocyanine (PIC) J aggregates produced at mica/solution interfaces have been characterized by absorption/fluorescence spectroscopy, fluorescence microscopy, and atomic force microscopy. Addition of organic s... |
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Organic cation transporter inhibition increases medial hypothalamic serotonin under basal conditions and during mild restraint
Brain Res. 1326 , 105-13, (2010) The dorsomedial hypothalamus (DMH) has been implicated in the coordination of stress responses. Restraint stress or systemic corticosterone (CORT) treatment induces a rapid increase in tissue concentrations of serotonin (5-hydroxytryptamine; 5-HT) in the DMH.... |
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The contribution of low-affinity transport mechanisms to serotonin clearance in synaptosomes.
Synapse 65(10) , 1015-23, (2011) Although many studies assert that the serotonin (5-HT) transporter (SERT) is the predominant mechanism controlling extracellular 5-HT concentrations, accumulating evidence suggests that low affinity, high capacity transport mechanisms may contribute more to 5... |