腺苷5'-二磷酸核糖钠盐
腺苷5'-二磷酸核糖钠盐结构式
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常用名 | 腺苷5'-二磷酸核糖钠盐 | 英文名 | Adenosine 5′-diphosphoribose sodium |
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| CAS号 | 68414-18-6 | 分子量 | 581.29800 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C15H22N5NaO14P2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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Aspirin inhibits expression of sFLT1 from human cytotrophoblasts induced by hypoxia, via cyclo-oxygenase 1.
Placenta 36(4) , 446-53, (2015) Elevated circulating soluble FLT1 (sFLT1) levels seen in preeclampsia may play a role in its development. Aspirin is recommended for prevention of preeclampsia. We hypothesized that aspirin may inhibit the production of sFlt1.Placentas from women with and wit... |
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Sclerotium rolfsii lectin induces stronger inhibition of proliferation in human breast cancer cells than normal human mammary epithelial cells by induction of cell apoptosis.
PLoS ONE 9(11) , e110107, (2014) Sclerotium rolfsii lectin (SRL) isolated from the phytopathogenic fungus Sclerotium rolfsii has exquisite binding specificity towards O-linked, Thomsen-Freidenreich (Galβ1-3GalNAcα1-Ser/Thr, TF) associated glycans. This study investigated the influence of SRL... |
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Alpha-fetoprotein, identified as a novel marker for the antioxidant effect of placental extract, exhibits synergistic antioxidant activity in the presence of estradiol.
PLoS ONE 9(6) , e99421, (2014) Placenta, as a reservoir of nutrients, has been widely used in medical and cosmetic materials. Here, we focused on the antioxidant properties of placental extract and attempted to isolate and identify the main antioxidant factors. Porcine placental extracts w... |
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Auranofin induces apoptosis and necrosis in HeLa cells via oxidative stress and glutathione depletion.
Mol. Med. Report. 11(2) , 1428-34, (2014) Auranofin (Au), an inhibitor of thioredoxin reductase, is a known anti‑cancer drug. In the present study, the anti‑growth effect of Au on HeLa cervical cancer cells was examined in association with levels of reactive oxygen species (ROS) and glutathione (GSH)... |
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The chalcone compound isosalipurposide (ISPP) exerts a cytoprotective effect against oxidative injury via Nrf2 activation.
Toxicol. Appl. Pharmacol. 287 , 77-85, (2015) The chalcone compound isosalipurposide (ISPP) has been successfully isolated from the native Korean plant species Corylopsis coreana Uyeki (Korean winter hazel). However, the therapeutic efficacy of ISPP remains poorly understood. This study investigated whet... |
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The novel HDAC inhibitor AR-42-induced anti-colon cancer cell activity is associated with ceramide production.
Biochem. Biophys. Res. Commun. 463 , 545-50, (2015) In the current study, we investigated the potential activity of AR-42, a novel histone deacetylase (HDAC) inhibitor, against colon cancer cells. Our in vitro results showed that AR-42 induced ceramide production, exerted potent anti-proliferative and pro-apop... |
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Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway.
Oncotarget 5(14) , 5559-69, (2014) Usp5 is a deubiquitinase (DUB) previously shown to regulate unanchored poly-ubiquitin (Ub) chains, p53 transcriptional activity and double-strand DNA repair. In BRAF mutant melanoma cells, Usp5 activity was suppressed by BRAF inhibitor (vemurafenib) in sensit... |
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Dexmedetomidine increases tau phosphorylation under normothermic conditions in vivo and in vitro.
Neurobiol. Aging 36 , 2414-28, (2015) There is developing interest in the potential association between anesthesia and the onset and progression of Alzheimer's disease. Several anesthetics have, thus, been demonstrated to induce tau hyperphosphorylation, an effect mostly mediated by anesthesia-in... |
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Immunostimulatory polysaccharide isolated from the leaves of Diospyros kaki Thumb modulate macrophage via TLR2.
Int. J. Biol. Macromol. 79 , 971-82, (2015) The objective of this study was to investigate the immunostimulatory effects of a polysaccharide fraction from the leaves of Diospyros kaki Thumb (PLE0) and the molecular mechanism responsible for its action in RAW 264.7 macrophages as well as in vivo effects... |
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EGFR and HER2 signals play a salvage role in MEK1-mutated gastric cancer after MEK inhibition.
Int. J. Oncol. 47 , 499-505, (2015) Since the prognosis of unresectable advanced gastric cancer remains poor, novel therapeutic strategies are needed. Somatic MEK1 gene mutations have been reported as oncogenic activating mutations in gastric cancer, and MEK inhibitors can be effective against ... |