氟代五氯丙酮
氟代五氯丙酮结构式
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常用名 | 氟代五氯丙酮 | 英文名 | 4-Methylumbelliferyl-N-acetyl-ß-D-glucosaminide |
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| CAS号 | 37067-30-4 | 分子量 | 379.361 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 732.2±60.0 °C at 760 mmHg | |
| 分子式 | C18H21NO8 | 熔点 | 208-210 °C | |
| MSDS | 中文版 美版 | 闪点 | 396.6±32.9 °C |
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Tay-Sachs disease heterozygote detection: use of a centrifugal analyser for automation of hexosaminidase assays with two different artificial substrates.
J. Med. Genet. 28(2) , 101-9, (1991) An assay for measuring hexosaminidase A in serum and leucocytes is described in which a centrifugal analyser is used for automation of the enzyme assays after manual heat inactivation. The assay was used in a screening programme to identify heterozygotes for ... |
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TNFalpha-induced macrophage death via caspase-dependent and independent pathways.
Apoptosis 14(3) , 320-32, (2009) Macrophages are the principal source of TNFalpha, yet they are highly resistant to TNFalpha-mediated cell death. Previously, employing in vitro differentiated human macrophages, we showed that following the inhibition of NF-kappaB, TNFalpha-induced caspase-8 ... |
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A rapid method for detection of N-acetylglucosaminidase-type chitinase activity in crossed immunoelectrophoresis and sodium dodecyl sulfate-polyacrylamide gel electrophoresis gels using 4-methylumbelliferyl-N-acetyl-D-glucosaminide as substrate.
Electrophoresis 15(5) , 662-5, (1994) A method for the detection of N-acetylglucosaminidase (GlcNAcase) activity has been developed by using 4-methyl-umbelliferyl-N-acetyl-D-glucosaminide (4-MU-GlcNAc) as substrate in crossed immunoelectrophoresis (CIE) and sodium dodecyl sulfate-polyacrylamide g... |
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Fluorometric measurement of urinary N-acetyl-beta-D-glucosaminidase and its correlation to uremia.
Clin. Chim. Acta 160(2) , 123-7, (1986) A fluorometric endpoint method for determination of N-acetyl-beta-D-glucosaminidase (NAG, EC 3.2.1.30) activity in human urine is described. Random urine samples from uremic hospital patients and healthy volunteers were studied using 4-methylumbelliferyl-N-ac... |
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Amphotericin B stimulates secretion of beta-hexosaminidase from mouse adherent spleen cells.
Biochem. Int. 24(2) , 235-41, (1991) Secretion of the lysosomal enzyme hexosaminidase is induced by amphotericin B in mouse spleen adherent cells that show a significant increase in their candidacidal activity. The stimulation of beta-hexosaminidase is both time and dose dependent. Amphotericin ... |
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Biochemical characterization of beta-hexosaminidase in different biological specimens from eleven patients with GM2-gangliosidosis B1 variant.
J. Inherit. Metab. Dis. 14(5) , 715-20, (1991) GM2-gangliosidosis B1 variant is thought to be a rare disorder with a wide geographical and ethnic distribution. We report the biochemical findings obtained in different specimens from a group of 11 B1 variant patients originating from the north of Portugal. ... |
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Increase of intermediate forms of beta-N-acetylhexosaminidase during rat liver development and regeneration.
Int. J. Biochem. 23(2) , 215-9, (1991) 1. Rat liver beta-N-acetylhexosaminidase was separated into several different molecular forms by DEAE-cellulose chromatography. 2. The subunit composition of the isoenzymes, as well as the similarities to human hexosaminidases, were determined by using the sp... |
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Dynamic evidence for an extended subsite structure of the ligand combining site on wheat germ agglutinin: temperature-jump relaxation with fluorescence detection.
Biochemistry 22(20) , 4797-804, (1983) Temperature-jump relaxation methods have been used to study the binding kinetics of fluorescent 4-methylumbelliferyl glycosides of N-acetyl-beta-D-glucosamine and its beta (1 leads to 4)-linked di- and trisaccharides with wheat germ agglutinin. The mono- and ... |
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Fluorometric detection and estimation of fungal biomass on cultural heritage materials.
J. Microbiol. Methods 80(2) , 178-82, (2010) A wide variety of cultural heritage materials are susceptible to fungal deterioration. The paper, canvas, and stone constituents of our cultural heritage are subjected to harmful physical and chemical processes as they are slowly consumed by fungi. Remediatio... |
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Purification and characterization of N-acetylglucosaminidase from Trypanosoma cruzi.
Exp. Parasitol. 83(2) , 167-73, (1996) N-Acetyl-beta-D-glucosaminidase activity was recovered in cell-free extracts of Trypanosoma cruzi epimastigotes. This enzyme was identified on the basis of its ability to hydrolyze the fluorogenic substrate 4-methylumbelliferyl-N-acetyl-beta-D-glucosaminide. ... |