Propanedinitrile,2-(acetyloxy)-2-methyl-
Propanedinitrile,2-(acetyloxy)-2-methyl-结构式
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常用名 | Propanedinitrile,2-(acetyloxy)-2-methyl- | 英文名 | Propanedinitrile,2-(acetyloxy)-2-methyl- |
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| CAS号 | 7790-01-4 | 分子量 | 138.12400 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C6H6N2O2 | 熔点 | 69-71 ℃(lit.) | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS06 |
信号词 | Danger |
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Artesunate-enhanced apoptosis of human high-risk myelodysplastic cells induced by the DNA methyltransferase inhibitor decitabine.
Oncol. Lett. 9 , 2449-2454, (2015) The present study aimed to investigate whether artesunate (ART) could enhance the rate of apoptosis induced by decitabine (DAC) in the high-risk myelodysplastic syndrome (MDS) SKM-1 cell line, and examine the potential underlying mechanisms. The cytotoxicity ... |
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An efficient method for the immobilization of inulinase using new types of polymers containing epoxy groups.
J. Ind. Microbiol. Biotechnol. 42 , 985-96, (2015) New glycidyl methacrylate copolymers containing different numbers of epoxy groups were synthesized and used to develop effective procedures for inulinase immobilization. The beneficial characteristics of the carriers included a high degree of crosslinking, st... |
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The human NANOS3 gene contributes to lung tumour invasion by inducing epithelial-mesenchymal transition.
J. Pathol. 237 , 25-37, (2015) We have explored the role of the human NANOS3 gene in lung tumour progression. We show that NANOS3 is over-expressed by invasive lung cancer cells and is a prognostic marker for non-small cell lung carcinomas (NSCLCs). NANOS3 gene expression is restricted in ... |
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Interaction of Salmonella enterica Serovar Typhimurium with Intestinal Organoids Derived from Human Induced Pluripotent Stem Cells.
Infect. Immun. 83 , 2926-34, (2015) The intestinal mucosa forms the first line of defense against infections mediated by enteric pathogens such as salmonellae. Here we exploited intestinal "organoids" (iHOs) generated from human induced pluripotent stem cells (hIPSCs) to explore the interaction... |
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Developmental regulation and induction of cytochrome P450 2W1, an enzyme expressed in colon tumors.
PLoS ONE 10(4) , e0122820, (2015) Cytochrome P450 2W1 (CYP2W1) is expressed predominantly in colorectal and also in hepatic tumors, whereas the levels are insignificant in the corresponding normal human adult tissues. CYP2W1 has been proposed as an attractive target for colorectal cancer (CRC... |
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The role of Drosophila TNF Eiger in developmental and damage-induced neuronal apoptosis.
FEBS Lett. 589(8) , 871-9, (2015) Eiger, the sole Drosophila TNF-alpha homolog, causes ectopic apoptosis through JNK pathway activation. Yet, its role in developmental apoptosis remains unclear. eiger mutant flies are viable and fertile but display compromised elimination of oncogenic cells a... |
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Effect of Different In Vitro Aging Methods on Color Stability of a Dental Resin-Based Composite Using CIELAB and CIEDE2000 Color-Difference Formulas.
J. Esthet. Restor. Dent. 27 , 322-30, (2015) To evaluate the effect of different in vitro aging methods on color change (CC) of an experimental dental resin-based composite using CIELAB (ΔEab ) and CIEDE2000 (ΔE00 ) color-difference formulas.The CC was evaluated with a spectrophotometer (CM700d, Konica ... |
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Decitabine nanoconjugate sensitizes human glioblastoma cells to temozolomide.
Mol. Pharm. 12(4) , 1279-88, (2015) In this study, we developed and characterized a delivery system for the epigenetic demethylating drug, decitabine, to sensitize temozolomide-resistant human glioblastoma multiforme (GBM) cells to alkylating chemotherapy. A poly(lactic-co-glycolic acid) (PLGA)... |
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Lgr5 Methylation in Cancer Stem Cell Differentiation and Prognosis-Prediction in Colorectal Cancer.
PLoS ONE 10 , e0143513, (2015) Leucine-rich-repeat-containing G-protein-coupled receptor 5 (lgr5) is a candidate marker for colorectal cancer stem cells (CSC). In the current study, we investigated the methylation status within thelgr5 promoter and evaluated its relationship with CSC diffe... |
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Aberrant TET1 Methylation Closely Associated with CpG Island Methylator Phenotype in Colorectal Cancer.
Cancer Prev. Res. (Phila.) 8 , 702-11, (2015) Inactivation of methylcytosine dioxygenase, ten-eleven translocation (TET) is known to be associated with aberrant DNA methylation in cancers. Tumors with a CpG island methylator phenotype (CIMP), a distinct subgroup with extensive DNA methylation, show chara... |