甲基环戊烯醇酮
甲基环戊烯醇酮结构式
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常用名 | 甲基环戊烯醇酮 | 英文名 | Methyl cyclopentenolone |
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| CAS号 | 80-71-7 | 分子量 | 112.127 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 212.2±40.0 °C at 760 mmHg | |
| 分子式 | C6H8O2 | 熔点 | 104-108°C | |
| MSDS | 中文版 美版 | 闪点 | 84.4±19.9 °C | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger |
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Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.
J. Med. Chem. 48 , 2906-15, (2005) Carboxylesterases (CE) are ubiquitous enzymes responsible for the metabolism of xenobiotics. Because the structural and amino acid homology among esterases of different classes, the identification of selective inhibitors of these proteins has proved problemat... |
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3-methyl-1,2-cyclopentanedione down-regulates age-related NF-kappaB signaling cascade.
J. Agric. Food Chem. 55(16) , 6787-92, (2007) Activation of the redox-sensitive transcription factor, nuclear factor-kappa B (NF-kappaB), plays a central role in inflammation and aging processes by inducing pro-inflammatory genes. The present study was designed to unravel the molecular mechanisms underly... |
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Enantiomeric deoxycholic acid: total synthesis, characterization, and preliminary toxicity toward colon cancer cell lines.
J. Org. Chem. 72(24) , 9298-307, (2007) Deoxycholic acid (DCA) is an endogenous secondary bile acid implicated in numerous pathological conditions including colon cancer formation and progression and cholestatic liver disease. DCA involvement in these disease processes results partly from its abili... |
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Selective peroxynitrite scavenging activity of 3-methyl-1,2-cyclopentanedione from coffee extract.
J. Pharm. Pharmacol. 54(10) , 1385-92, (2002) It has been known that reactive oxygen and nitrogen species such as nitric oxide (NO), superoxide radical (*O2-) and their byproduct peroxynitrite (ONOO-) induce cellular and tissue injury, ultimately resulting in several human diseases. In this study, we exa... |
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Peroxisome proliferator-activated receptor gamma agonist action of 3-methyl-1,2-cyclopentanedione.
Biochim. Biophys. Acta 1770(12) , 1612-9, (2007) Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily that plays a pivotal role in regulating inflammatory gene expression. The purpose of this study was to investigate the effects of coffee extract, 3-met... |