2,6-二羟基吡啶盐酸
2,6-二羟基吡啶盐酸结构式
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常用名 | 2,6-二羟基吡啶盐酸 | 英文名 | 2,6-pyridinediol, hydrochloride |
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| CAS号 | 10357-84-3 | 分子量 | 147.560 | |
| 密度 | 1.379g/cm3 | 沸点 | 387.2ºC at 760mmHg | |
| 分子式 | C5H6ClNO2 | 熔点 | 206-208 °C (dec.)(lit.) | |
| MSDS | 美版 | 闪点 | 188ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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[Estimation of pathways of 5-fluorouracil anabolism in human cancer cells in vitro and in vivo].
Gan To Kagaku Ryoho. 23(6) , 721-31, (1996) Possible pathways of intracellular phosphorylation of 5-fluorouracil (5-FU) in human cancer cells were investigated in vitro and in vivo. We used two inhibitors which regulate the anabolism of 5-FU for the purpose of elucidation of its pathways; one is oxonic... |
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An alpha/beta-fold C--C bond hydrolase is involved in a central step of nicotine catabolism by Arthrobacter nicotinovorans.
J. Bacteriol. 187(24) , 8516-9, (2005) The enzyme catalyzing the hydrolytic cleavage of 2,6-dihydroxypseudooxynicotine to 2,6-dihydroxypyridine and gamma-N-methylaminobutyrate was found to be encoded on pAO1 of Arthrobacter nicotinovorans. The new enzyme answers an old question about nicotine cata... |
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Combination of the chemotherapeutic agent 5-fluorouracil with an inhibitor of its catabolism results in increased micronucleus induction.
Biochem. Biophys. Res. Commun. 203(2) , 1124-30, (1994) The rate limiting step in 5-fluorouracil catabolism is catalyzed by the enzyme dihydropyrimidine dehydrogenase. Since degradation of 5-fluorouracil decreases its efficacy in chemotherapy, the inhibition of its catabolism is a promising tool. We investigated t... |