反式-2-戊烯酸
反式-2-戊烯酸结构式
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常用名 | 反式-2-戊烯酸 | 英文名 | trans-2-pentenoic acid |
|---|---|---|---|---|
| CAS号 | 13991-37-2 | 分子量 | 100.11600 | |
| 密度 | 0.99 g/mL at 25 °C(lit.) | 沸点 | 106 °C20 mm Hg(lit.) | |
| 分子式 | C5H8O2 | 熔点 | 9-11 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 102 °C | |
| 符号 |
GHS05, GHS07 |
信号词 | Danger |
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Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs.
FASEB J. 26 , 4951-65, (2012) When it is difficult to develop selective ligands within a family of related G-protein-coupled receptors (GPCRs), chemically engineered receptors activated solely by synthetic ligands (RASSLs) are useful alternatives for probing receptor function. In the pres... |
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Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).
Bioorg. Med. Chem. Lett. 21 , 2736-9, (2011) Nicotinic acid (niacin) has been used for decades as an antidyslipidemic drug in man. Its main target is the hydroxy-carboxylic acid receptor HCA2 (GPR109A), a G protein-coupled receptor. Other acids and esters such as methyl fumarate also interact with the r... |
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Switching androgen receptor antagonists to agonists by modifying C-ring substituents on piperidino[3,2-g]quinolinone.
Bioorg. Med. Chem. Lett. 9(7) , 1009-12, (1999) New nonsteroidal human androgen receptor (hAR) agonists were developed from an hAR antagonist pharmacophore, 2(1H)-piperidino[3,2-g]quinolinone. (+/-)-trans-7,8-Diethyl-4-trifluoromethyl-2(H)-piperidino-[3,2-g]quinoli none was synthesized and demonstrated pot... |
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Structure-activity relationship of cinnamaldehyde analogs as inhibitors of AI-2 based quorum sensing and their effect on virulence of Vibrio spp.
PLoS ONE 6(1) , e16084, (2011) Many bacteria, including Vibrio spp., regulate virulence gene expression in a cell-density dependent way through a communication process termed quorum sensing (QS). Hence, interfering with QS could be a valuable novel antipathogenic strategy. Cinnamaldehyde h... |
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Production of functionalized polyhydroxyalkanoates by genetically modified Methylobacterium extorquens strains.
Microb. Cell Fact. 9 , 70, (2010) Methylotrophic (methanol-utilizing) bacteria offer great potential as cell factories in the production of numerous products from biomass-derived methanol. Bio-methanol is essentially a non-food substrate, an advantage over sugar-utilizing cell factories. Low-... |