PARP1-IN-11

Modify Date: 2024-04-08 13:51:35

PARP1-IN-11 structure	Common Name	PARP1-IN-11
	CAS Number	2482484-87-5	Molecular Weight	296.28
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₂N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PARP1-IN-11

PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC50 value of 0.082 µM. PARP1-IN-11 shows complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1 and TNKS2[1].

Name	PARP1-IN-11

Description	PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC50 value of 0.082 µM. PARP1-IN-11 shows complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1 and TNKS2[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	PARP1:0.082 μM (IC50) PARP2 TNKS1 TNKS2
References	[1]. Shao X, et al. Synthesis of 2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide and 3-oxo-3,4-dihydrobenzo[b][1,4]oxazine-8-carboxamide derivatives as PARP1 inhibitors. Bioorg Chem. 2020 Sep;102:104075.

Molecular Formula	C₁₆H₁₂N₂O₄
Molecular Weight	296.28