ALDH1A1-IN-3

Modify Date: 2024-01-14 16:00:48

ALDH1A1-IN-3 Structure
ALDH1A1-IN-3 structure
Common Name ALDH1A1-IN-3
CAS Number 2439177-97-4 Molecular Weight 599.64
Density N/A Boiling Point N/A
Molecular Formula C31H36F3N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ALDH1A1-IN-3


ALDH1A1-IN-3 (compound 57) is an excellent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor with an IC50 value of 0.379 μM. ALDH1A1-IN-3 can effectively improve glucose consumption in HepG2 cells. ALDH1A1-IN-3 can be used for researching glucose metabolism improvement[1].

 Names

Name ALDH1A1-IN-3

 ALDH1A1-IN-3 Biological Activity

Description ALDH1A1-IN-3 (compound 57) is an excellent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor with an IC50 value of 0.379 μM. ALDH1A1-IN-3 can effectively improve glucose consumption in HepG2 cells. ALDH1A1-IN-3 can be used for researching glucose metabolism improvement[1].
Related Catalog
Target

IC50: 0.379 μM (ALDH1A1)[1]

References

[1]. Ma Z, et al. Design, synthesis of 1,3-dimethylpyrimidine-2,4-diones as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity. Bioorg Chem. 2020 Aug;101:103971.

 Chemical & Physical Properties

Molecular Formula C31H36F3N5O4
Molecular Weight 599.64