Melatonin receptor agonist 1

Modify Date: 2024-01-13 06:58:09

Melatonin receptor agonist 1 structure	Common Name	Melatonin receptor agonist 1
	CAS Number	2411150-76-8	Molecular Weight	273.33
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₉N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Melatonin receptor agonist 1

Melatonin receptor agonist 1 (compound 20c) is a potent melatonin receptor (MT) agonist, with Ki values of 108 nM (MT2) and 1140 nM (MT1)[1].

Name	Melatonin receptor agonist 1

Description	Melatonin receptor agonist 1 (compound 20c) is a potent melatonin receptor (MT) agonist, with Ki values of 108 nM (MT2) and 1140 nM (MT1)[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Melatonin Receptor Signaling Pathways >> GPCR/G Protein >> Melatonin Receptor Research Areas >> Neurological Disease
Target	MT2:108 nM (Ki) MT1:1140 nM (Ki)
In Vitro	Melatonin receptor agonist 1 (compound 20c) shows a 10 times MT2-selectivity over MT1[1].
References	[1]. Bolteau R, et al. Quinazoline and phthalazine derivatives as novel melatonin receptor ligands analogues of agomelatine. Eur J Med Chem. 2020 Mar 1;189:112078.

Molecular Formula	C₁₅H₁₉N₃O₂
Molecular Weight	273.33