1678501-16-0

1678501-16-0 structure

Name: mGlu4 receptor agonist 1
Chemical Name: mGlu4 receptor agonist 1
CAS Number: 1678501-16-0
Molecular Formula: C₂₁H₁₅ClN₄O₂
Molecular Weight: 390.82
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2022-06-27 06:20:32
Modify Date: 2025-09-02 21:04:53
mGlu4 receptor agonist 1 (compound 62) is a potent mGlu4 receptor positive allosteric modulator, with an EC50 of 308 nM. mGlu4 receptor agonist 1 shows significant anxiolytic- and antipsychotic-like effect[1].

Name	mGlu4 receptor agonist 1

Description	mGlu4 receptor agonist 1 (compound 62) is a potent mGlu4 receptor positive allosteric modulator, with an EC50 of 308 nM. mGlu4 receptor agonist 1 shows significant anxiolytic- and antipsychotic-like effect[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR4:308 ± 35 nM (EC50)
References	[1]. Stankiewicz A, et al. New 1,2,4-oxadiazole derivatives with positive mGlu4 receptor modulation activity and antipsychotic-like properties. J Enzyme Inhib Med Chem. 2022 Dec;37(1):211-225.

Molecular Formula	C₂₁H₁₅ClN₄O₂
Molecular Weight	390.82