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2411150-76-8

2411150-76-8 structure

2411150-76-8 structure

Name: Melatonin receptor agonist 1
Chemical Name: Melatonin receptor agonist 1
CAS Number: 2411150-76-8
Molecular Formula: C₁₅H₁₉N₃O₂
Molecular Weight: 273.33
Catalog: Signaling Pathways GPCR/G Protein Melatonin Receptor
Create Date: 2022-06-26 09:32:23
Modify Date: 2025-08-26 20:54:51
Melatonin receptor agonist 1 (compound 20c) is a potent melatonin receptor (MT) agonist, with Ki values of 108 nM (MT2) and 1140 nM (MT1)[1].

Name	Melatonin receptor agonist 1

Description	Melatonin receptor agonist 1 (compound 20c) is a potent melatonin receptor (MT) agonist, with Ki values of 108 nM (MT2) and 1140 nM (MT1)[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Melatonin Receptor Signaling Pathways >> GPCR/G Protein >> Melatonin Receptor Research Areas >> Neurological Disease
Target	MT2:108 nM (Ki) MT1:1140 nM (Ki)
In Vitro	Melatonin receptor agonist 1 (compound 20c) shows a 10 times MT2-selectivity over MT1[1].
References	[1]. Bolteau R, et al. Quinazoline and phthalazine derivatives as novel melatonin receptor ligands analogues of agomelatine. Eur J Med Chem. 2020 Mar 1;189:112078.

Molecular Formula	C₁₅H₁₉N₃O₂
Molecular Weight	273.33

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