ACC1/2-IN-1

Modify Date: 2024-01-17 13:44:27

ACC1/2-IN-1 structure	Common Name	ACC1/2-IN-1
	CAS Number	2350219-22-4	Molecular Weight	560.64
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₄H₃₂N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ACC1/2-IN-1

ACC1/2-IN-1 (compound 4s) is a potent ACC1/2 inhibitor with IC50 values of 98.06 and 29.43 nM for ACC1 and ACC2, respectively. ACC1/2-IN-1 can be used for cancer research[1].

Name	ACC1/2-IN-1

Description	ACC1/2-IN-1 (compound 4s) is a potent ACC1/2 inhibitor with IC50 values of 98.06 and 29.43 nM for ACC1 and ACC2, respectively. ACC1/2-IN-1 can be used for cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Acetyl-CoA Carboxylase
In Vitro	ACC1/2-IN-1 (compound 4s) (72 hours; tumor cell lines) has anti-proliferative activity against A549, H1975, HCT116 and H7901 cell lines with IC50 values of 0.578, 1.005, 0.680 and 1.406 μΜ, respectively[1].
References	[1]. Wei Q, et al. Design, synthesis and biological evaluation of novel chroman derivatives as non-selective acetyl-CoA carboxylase inhibitors. Bioorg Chem. 2020 Aug;101:103943.

Molecular Formula	C₃₄H₃₂N₄O₄
Molecular Weight	560.64