942425-34-5

942425-34-5 structure
942425-34-5 structure
  • Name: PKN1/2-IN-1
  • Chemical Name: PKN1/2-IN-1
  • CAS Number: 942425-34-5
  • Molecular Formula: C14H15N3O
  • Molecular Weight: 241.29
  • Create Date: 2022-05-20 10:24:51
  • Modify Date: 2025-11-07 18:30:42
  • PKN1/2-IN-1 is a potent, cell penetrant and selective PKN2 (PRK2) inhibitor (IC50=16 nM; Ki=8 nM)[1].

Name PKN1/2-IN-1
Description PKN1/2-IN-1 is a potent, cell penetrant and selective PKN2 (PRK2) inhibitor (IC50=16 nM; Ki=8 nM)[1].
Related Catalog
Target

IC50: 16 nM, Ki: 8 nM (PKN2)[1] IC50: 108 nM, Ki: 210 nM (PKN1)[1].

References

[1]. Scott F, et al. Development of dihydropyrrolopyridinone-based PKN2/PRK2 chemical tools to enable drug discovery. Bioorg Med Chem Lett. 2022;60:128588.

Molecular Formula C14H15N3O
Molecular Weight 241.29
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