mGluR2 modulator 3

Modify Date: 2025-08-25 19:36:40

mGluR2 modulator 3 Structure
mGluR2 modulator 3 structure
Common Name mGluR2 modulator 3
CAS Number 1004614-58-7 Molecular Weight 335.44
Density N/A Boiling Point N/A
Molecular Formula C21H25N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of mGluR2 modulator 3


mGluR2 modulator 3 (compound 1) is a potent mGluR2 positive allosteric modulator with an EC50 value of 0.87 μM. mGluR2 modulator 3 has activity in psychosis disease models such as methamphetamine-induced hyperactivity and mescaline-induced scratching in mice[1].

 Names

Name mGluR2 modulator 3

 mGluR2 modulator 3 Biological Activity

Description mGluR2 modulator 3 (compound 1) is a potent mGluR2 positive allosteric modulator with an EC50 value of 0.87 μM. mGluR2 modulator 3 has activity in psychosis disease models such as methamphetamine-induced hyperactivity and mescaline-induced scratching in mice[1].
Related Catalog
Target

mGluR2:0.87 μM (EC50)

References

[1]. Szabó G, et al. Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs). Eur J Med Chem. 2020;186:111881.

 Chemical & Physical Properties

Molecular Formula C21H25N3O
Molecular Weight 335.44
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