2476490-18-1

2476490-18-1 structure

Name: PCSK9 modulator-3
Chemical Name: PCSK9 modulator-3
CAS Number: 2476490-18-1
Molecular Formula: C₁₆H₉F₂N₃O
Molecular Weight: 297.26
Catalog: Research Areas Metabolic Disease
Create Date: 2022-07-02 12:10:31
Modify Date: 2024-01-09 17:56:22
PCSK9 modulator-3 (Compound 13) is a potent modulator of PCSK9 with an EC50 value of 2.46 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-3 has the potential for the research of hyperlipidemia[1].

Name	PCSK9 modulator-3

Description	PCSK9 modulator-3 (Compound 13) is a potent modulator of PCSK9 with an EC50 value of 2.46 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-3 has the potential for the research of hyperlipidemia[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Xie H, et al. From methylene bridged diindole to carbonyl linked benzimidazoleindole: Development of potent and metabolically stable PCSK9 modulators. Eur J Med Chem. 2020 Nov 15;206:112678.

Molecular Formula	C₁₆H₉F₂N₃O
Molecular Weight	297.26