2671063-84-4

2671063-84-4 structure

Name: mGluR2 modulator 1
Chemical Name: mGluR2 modulator 1
CAS Number: 2671063-84-4
Molecular Formula: C₂₁H₂₀F₃N₃O₃
Molecular Weight: 419.40
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2022-07-01 20:39:55
Modify Date: 2025-08-25 19:07:39
mGluR2 modulator 1 (compound 95) is a potent and BBB-penetrated mGluR2 (metabotropic glutamate receptor-2) positive allosteric modulator, with an EC50 of 0.03 μM. mGluR2 modulator 1 can be used for psychosis research[1].

Name	mGluR2 modulator 1

Description	mGluR2 modulator 1 (compound 95) is a potent and BBB-penetrated mGluR2 (metabotropic glutamate receptor-2) positive allosteric modulator, with an EC50 of 0.03 μM. mGluR2 modulator 1 can be used for psychosis research[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR2:0.03 ± 0.0 μM (EC50)
References	[1]. Szabó G, et al. Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs). Eur J Med Chem. 2020 Jan 15;186:111881.

Molecular Formula	C₂₁H₂₀F₃N₃O₃
Molecular Weight	419.40