GPR39 modulator 3
Modify Date: 2024-01-19 23:30:25
GPR39 modulator 3 structure
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Common Name | GPR39 modulator 3 | ||
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| CAS Number | 1582736-28-4 | Molecular Weight | 528.642 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 736.1±70.0 °C at 760 mmHg | |
| Molecular Formula | C26H33FN6O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 399.0±35.7 °C | |
Use of GPR39 modulator 3GPR39 modulator 3 is a Hedgehog pathway inhibitor that has high cellular potency (EC50=5 nM) in the reporter gene assay, activates the orphan receptor GPR39 and potently reduces of Gli1 and Ptch1 mRNA levels; activates the orphan receptor GPR39, which signals to the Gli transcription factors and blocks signaling; a useful chemical tool for in vitro interrogation of GPR39 signaling in different cellular contexts. |
| Name | 4-Fluoro-N-({trans-4-[({4-[(2-methoxyethyl)amino]-6-(2-pyridinyl)-2-pyrimidinyl}amino)methyl]cyclohexyl}methyl)benzenesulfonamide |
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| Synonym | More Synonyms |
| Description | GPR39 modulator 3 is a Hedgehog pathway inhibitor that has high cellular potency (EC50=5 nM) in the reporter gene assay, activates the orphan receptor GPR39 and potently reduces of Gli1 and Ptch1 mRNA levels; activates the orphan receptor GPR39, which signals to the Gli transcription factors and blocks signaling; a useful chemical tool for in vitro interrogation of GPR39 signaling in different cellular contexts. |
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| References | References 1. Bassilana F, et al. Nat Chem Biol. 2014 May;10(5):343-9. View Related Products by Target GPR39 |
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 736.1±70.0 °C at 760 mmHg |
| Molecular Formula | C26H33FN6O3S |
| Molecular Weight | 528.642 |
| Flash Point | 399.0±35.7 °C |
| Exact Mass | 528.231873 |
| LogP | 2.68 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.589 |
| 4-Fluoro-N-(((1r,4r)-4-(((4-((2-methoxyethyl)amino)-6-(pyridin-2-yl)pyrimidin-2-yl)amino)methyl)cyclohexyl)methyl)benzenesulfonamide |
| 4-Fluoro-N-({trans-4-[({4-[(2-methoxyethyl)amino]-6-(2-pyridinyl)-2-pyrimidinyl}amino)methyl]cyclohexyl}methyl)benzenesulfonamide |
| Benzenesulfonamide, 4-fluoro-N-[[trans-4-[[[4-[(2-methoxyethyl)amino]-6-(2-pyridinyl)-2-pyrimidinyl]amino]methyl]cyclohexyl]methyl]- |